Mastering the Chemical Brow Lift and Under-Eye Combination: The Perfect Pair for Complete Eye Rejuvenation

Introduction: The Synergy of Upper and Lower Eye Rejuvenation

The eyes represent the most expressive and noticed feature of the face, often revealing signs of aging, stress, and fatigue before other areas. While many aesthetic treatments focus on either the upper or lower eye region independently, a growing body of clinical evidence suggests that comprehensive rejuvenation requires addressing both areas simultaneously.

The Chemical Brow Lift has emerged as one of London’s most sought-after treatments for its ability to create a refreshed, more alert appearance through precise muscle relaxation. However, its benefits can be significantly enhanced when paired with targeted under-eye treatments that address complementary concerns in the lower orbital area.

At Mesglo London, our Marylebone specialists have pioneered advanced combination approaches that synchronize these treatments for harmonious, natural-looking results. This comprehensive guide explores the science behind this powerful pairing, the specific techniques that maximize their synergy, and the transformative outcomes possible when these treatments work in concert.

Understanding the Eye Region: A Unified Aesthetic Unit

To appreciate why combining Chemical Brow Lift with under-eye treatments creates superior results, we must first understand how the eye region functions as an integrated aesthetic unit.

The Anatomical Connection

The upper and lower eye regions share intimate anatomical relationships:

•Orbital Continuity: The orbital rim forms a continuous structure surrounding the eye

•Muscle Interactions: The orbicularis oculi muscle encircles the entire eye

•Fat Pad Relationships: Upper and lower orbital fat compartments connect at the lateral canthus

•Skin Quality Continuity: Periorbital skin shares similar characteristics throughout

•Vascular Network: Shared blood supply throughout the periorbital region

•Lymphatic Drainage: Interconnected drainage pathways affecting both regions

These anatomical connections mean that changes in one area inevitably influence the appearance of the other—a principle that forms the foundation for combination approaches.

The Aging Process: Upper and Lower Manifestations

Aging affects the entire eye region through related but distinct processes:

Aging Change	Upper Eye Manifestation	Lower Eye Manifestation	Combined Effect
Muscle Hyperactivity	Brow depression, hooding	Under-eye muscle bands	Tired, aged appearance
Volume Loss	Temple hollowing, brow support loss	Tear trough formation, fat pad descent	Skeletal, hollow look
Skin Changes	Upper eyelid crepiness, hooding	Under-eye fine lines, crepiness	Overall aged skin quality
Fat Redistribution	Upper eyelid fat prolapse	Under-eye bags, malar fat pad descent	Puffy, heavy appearance
Bone Resorption	Brow bone recession	Infraorbital rim flattening	Support structure loss
Ligament Laxity	Brow ptosis	Tear trough deepening, mid-face descent	Overall structural descent

Research published in the Aesthetic Surgery Journal demonstrates that addressing only one aspect of these changes typically yields incomplete improvement, while comprehensive approaches create more harmonious, natural-looking rejuvenation.

The Perception Connection

Beyond anatomy, human perception naturally processes the eye region as a unified whole:

•Gaze Patterns: Eye-tracking studies show observers scan the entire eye region rather than focusing on isolated areas

•Emotional Reading: We interpret emotions based on the relationship between upper and lower eye positions

•Age Perception: Studies show age estimation relies heavily on the overall eye region appearance

•Attention Focus: The eye region receives more visual attention than any other facial feature

•Harmony Assessment: Observers unconsciously evaluate facial harmony based on proportional relationships

This perceptual reality means that optimal aesthetic results require balanced enhancement of both regions rather than isolated treatment of either area alone.

The Chemical Brow Lift: Foundation for Upper Eye Rejuvenation

Before exploring combination approaches, it’s important to understand the core benefits and mechanisms of the Chemical Brow Lift as the foundation for upper eye enhancement.

Mechanism of Action

The Chemical Brow Lift creates improvement through sophisticated muscle modulation:

•Selective Relaxation: Precisely targets specific depressor muscles that pull the brow downward

•Balance Preservation: Maintains frontalis function for natural brow elevation

•Lateral Emphasis: Creates greater lateral than medial lift for natural-looking results

•Muscle Retraining: Gradually modifies muscle patterns for sustained improvement

•Dynamic Preservation: Maintains appropriate expressiveness while reducing downward pull

•Progressive Effect: Develops gradually for natural-looking enhancement

This precise approach creates subtle but significant improvement in upper eye appearance without surgery or downtime.

Primary Benefits for the Upper Eye Region

The Chemical Brow Lift delivers several key improvements to the upper eye area:

•Brow Elevation: Typically 2-4mm of lift, primarily in the lateral brow

•Upper Eyelid Space: Increased visible eyelid, creating a more open-eyed appearance

•Reduced Hooding: Diminished heaviness at the lateral eyelid

•Smoother Forehead: Reduced dynamic lines when expressing

•Refreshed Appearance: More alert, less tired look

•Softened Expression: Reduced appearance of anger, concern, or fatigue

These benefits address many common upper eye concerns, but for comprehensive rejuvenation, the lower eye region requires complementary attention.

Limitations When Used Alone

Despite its benefits, the Chemical Brow Lift alone cannot address:

•Tear Trough Depressions: The hollow area beneath the eye

•Under-Eye Circles: Darkness or discoloration beneath the eye

•Lower Eyelid Crepiness: Fine lines and skin quality issues

•Infraorbital Hollowing: Volume loss in the under-eye area

•Malar Festoons: Fluid accumulation in the upper cheek

•Lower Lid Position: Structural support of the lower eyelid

These limitations highlight why combination approaches yield superior comprehensive results compared to isolated treatments.

Under-Eye Treatments: Complementary Lower Eye Enhancement

Several sophisticated under-eye treatments can complement the Chemical Brow Lift, each addressing specific aspects of lower eye aging.

Tear Trough Filler: Structural Support and Volume Restoration

Specialized filler techniques for the tear trough area provide structural improvement:

Treatment Basics:

•Mechanism: Strategic placement of dermal fillers to restore volume and support

•Approach: Deep placement along the orbital rim and tear trough

•Duration: 15-30 minute treatment session

•Anesthesia: Topical numbing cream

•Longevity: 9-18 months depending on product and metabolism

Key Benefits:

•Reduces hollow appearance beneath the eyes

•Diminishes shadow casting that creates dark circles

•Improves transition between lower lid and cheek

•Creates structural support for the lower eyelid

•Restores youthful midface contours

Ideal Candidates:

•Patients with visible tear trough depressions

•Those with hollowing rather than puffiness

•Individuals with good skin quality

•Patients without significant lower lid laxity

•Those seeking non-surgical improvement

Skin Boosters: Quality Enhancement for Delicate Under-Eye Skin

Advanced skin booster treatments address the unique needs of periorbital skin:

Treatment Basics:

•Mechanism: Micro-injection of hydrating agents and skin-building compounds

•Approach: Superficial placement in a specific pattern

•Duration: 15-20 minute treatment session

•Anesthesia: Topical numbing cream

•Longevity: 4-6 months with cumulative improvement

Key Benefits:

•Improves skin hydration and elasticity

•Reduces fine lines and crepiness

•Enhances overall skin quality and luminosity

•Strengthens dermal structure

•Creates subtle improvement in skin thickness

Ideal Candidates:

•Patients with fine lines and crepiness

•Those with thin, dehydrated under-eye skin

•Individuals seeking skin quality improvement

•Patients with early signs of aging

•Those wanting preventative treatment

PRP and Exosome Therapy: Regenerative Approaches

Cutting-edge regenerative treatments offer progressive improvement:

Treatment Basics:

•Mechanism: Application of growth factors and regenerative compounds

•Approach: Injection or microneedling delivery

•Duration: 30-45 minute treatment session

•Anesthesia: Topical numbing cream

•Longevity: 4-6 months with cumulative effects

Key Benefits:

•Stimulates collagen and elastin production

•Improves microcirculation

•Enhances cellular renewal

•Reduces pigmentation issues

•Creates progressive, natural improvement

Ideal Candidates:

•Patients seeking natural, progressive results

•Those with multiple under-eye concerns

•Individuals wanting preventative treatment

•Patients preferring regenerative approaches

•Those with mild to moderate concerns

Light Energy Devices: Targeted Improvement for Specific Concerns

Various energy-based treatments address particular under-eye issues:

Treatment Basics:

•Mechanism: Controlled energy delivery to stimulate specific responses

•Approach: Non-invasive or minimally invasive application

•Duration: 15-30 minute treatment session

•Anesthesia: Typically none required

•Longevity: Variable based on technology and concern

Key Benefits:

•Reduces pigmentation in dark circles

•Tightens mild skin laxity

•Improves vascular causes of discoloration

•Enhances overall skin texture

•Creates controlled collagen stimulation

Ideal Candidates:

•Patients with specific concerns like pigmentation

•Those seeking non-injectable options

•Individuals with good overall skin quality

•Patients wanting preventative treatment

•Those with mild to moderate concerns

The Synergy Effect: Why Combination Creates Superior Results

The combination of Chemical Brow Lift with under-eye treatments creates results that exceed what either approach can achieve independently.

The Structural Balance Principle

Comprehensive eye rejuvenation requires balanced structural enhancement:

•Vertical-Horizontal Balance: Brow lift creates vertical improvement while under-eye treatments address horizontal planes

•Upper-Lower Proportion: Restores proper relationship between upper and lower orbital areas

•Dynamic-Static Harmony: Combines muscle modulation with structural support

•Light-Shadow Interplay: Reduces shadow casting through complementary approaches

•Tissue-Support Relationship: Addresses both tissue position and underlying support

•Muscle-Volume Interaction: Balances muscle activity with appropriate volume distribution

This multi-dimensional approach creates more harmonious, natural-looking results than addressing either area in isolation.

The Visual Perception Enhancement

Combined treatments create superior perceptual improvement:

•Expanded Eye Frame: Creates a more open, alert appearance from all angles

•Reduced Age Signaling: Simultaneously addresses multiple age indicators

•Enhanced Expressiveness: Improves positive expression while reducing negative cues

•Balanced Rejuvenation: Prevents the disharmony of treating only one region

•Comprehensive Refreshment: Creates overall impression of vitality and rest

•Natural Transition Zones: Ensures smooth transitions between facial regions

Research in facial perception demonstrates that observers rate combined treatments significantly higher than isolated approaches in terms of perceived youthfulness, attractiveness, and naturalness.

The Technical Advantage

From a technical perspective, combination approaches offer several advantages:

•Complementary Mechanisms: Different treatment modalities address distinct aspects of aging

•Reduced Overcorrection Risk: Less need to overtreat any single area

•Enhanced Longevity: Combined treatments often extend the duration of results

•Optimized Outcomes: Each treatment performs better in the context of the other

•Customization Potential: Allows precise tailoring to individual needs

•Progressive Improvement: Creates both immediate and long-term benefits

These technical synergies translate to superior clinical outcomes with more natural-looking, harmonious results.

Specialized Combination Techniques: The Mesglo London Approach

At Mesglo Clinic in London, our specialists have developed sophisticated combination protocols that maximize the synergy between Chemical Brow Lift and under-eye treatments.

The Orbital Frame Technique

Our signature approach addresses the entire eye frame as a unified aesthetic unit:

Key Characteristics:

•360° Assessment: Comprehensive evaluation of the entire orbital region

•Prioritized Sequencing: Strategic ordering of treatments for optimal results

•Balanced Intervention: Proportional treatment of upper and lower regions

•Preservation Zones: Identification of areas requiring minimal or no treatment

•Transition Management: Special attention to junction areas between regions

•Expression Preservation: Maintenance of natural animation and character

Technical Elements:

•Precise Chemical Brow Lift with lateral emphasis

•Deep-plane tear trough treatment when appropriate

•Skin quality enhancement with targeted boosters

•Potential light energy treatment for specific concerns

•Customized home care protocol

This comprehensive approach creates harmonious, natural-looking rejuvenation of the entire eye region.

The Progressive Enhancement Protocol

For patients preferring a gradual, conservative approach:

Key Characteristics:

•Staged Implementation: Sequential treatment over multiple sessions

•Foundation First: Chemical Brow Lift as the initial treatment

•Response Assessment: Evaluation before adding complementary treatments

•Micro-Treatment Philosophy: Multiple subtle interventions rather than fewer significant ones

•Cumulative Improvement: Building results progressively over time

•Adjustment Opportunity: Refinement based on developing results

Technical Elements:

•Initial conservative Chemical Brow Lift

•Two-week assessment before under-eye treatment

•Micro-aliquot tear trough approach if appropriate

•Sequential skin quality treatments

•Regular reassessment and refinement

This measured approach is particularly valuable for first-time patients or those preferring the most subtle, natural-looking enhancement.

The Regenerative Combination

For patients seeking long-term improvement beyond immediate results:

Key Characteristics:

•Biological Stimulation: Focus on treatments that enhance natural regeneration

•Structural Foundation: Chemical Brow Lift combined with structural support

•Cellular Activation: Incorporation of growth factor treatments

•Progressive Protocol: Treatment plan designed for cumulative improvement

•Preventative Philosophy: Addressing current concerns while preventing future changes

•Holistic Integration: Complementary lifestyle and skincare recommendations

Technical Elements:

•Precision Chemical Brow Lift

•Exosome Treatment for under-eye region

•Potential Polynucleotide Therapy for skin quality

• Lumi Eyes treatment

•Strategic micro-volume replacement when needed

•Comprehensive home care protocol

This approach creates both immediate enhancement and progressive long-term improvement in the entire eye region.

Treatment Planning: Creating Your Personalized Combination

Effective combination treatment requires sophisticated planning tailored to individual needs.

The Comprehensive Assessment

Proper treatment planning begins with detailed evaluation:

•Dynamic Assessment: Observation of facial movement and expressions

•Static Analysis: Evaluation of structural relationships at rest

•Tissue Quality Evaluation: Assessment of skin, fat, and muscle characteristics

•Concern Prioritization: Identification of primary and secondary issues

•Anatomical Mapping: Precise documentation of key anatomical landmarks

•Treatment History Review: Understanding of previous interventions and responses

This thorough assessment forms the foundation for personalized treatment planning.

Sequencing Considerations

The order of treatments significantly impacts results:

Scenario	Recommended Sequence	Rationale
Standard Approach	Chemical Brow Lift first, under-eye treatment 2 weeks later	Allows brow position to stabilize before addressing lower region
Significant Tear Troughs	Tear trough treatment first, Chemical Brow Lift 2-4 weeks later	Establishes structural foundation before muscle modulation
Skin Quality Focus	Simultaneous Chemical Brow Lift and skin quality treatment	Addresses both concerns without interaction concerns
Comprehensive Rejuvenation	Chemical Brow Lift, assess at 2 weeks, under-eye treatment, final refinement at 4 weeks	Progressive approach with adjustment opportunities
Asymmetry Correction	Chemical Brow Lift, assess at 2 weeks, targeted under-eye treatment	Allows precise correction of remaining asymmetry

Proper sequencing ensures optimal results while minimizing the risk of complications or suboptimal outcomes.

Customization Factors

Several factors influence the specific combination approach:

•Age-Related Considerations: Different approaches for different age groups

•Anatomical Variations: Treatment adjusted for individual facial structure

•Skin Type and Quality: Protocols modified based on skin characteristics

•Previous Treatment History: Approach adjusted based on prior interventions

•Lifestyle Factors: Consideration of recovery time and social requirements

•Long-Term Goals: Planning for immediate and future enhancement

This personalized approach ensures optimal results for each individual’s unique situation.

The Treatment Experience: What to Expect

Understanding the practical aspects of combination treatment helps set appropriate expectations.

Preparation Guidelines

Proper preparation enhances safety and results:

•Pre-Treatment Recommendations:

•Avoid blood thinners (including certain supplements) for 7-10 days if medically appropriate

•Stay well-hydrated for 48 hours before treatment

•Avoid alcohol for 24 hours before treatment

•Arrive with clean skin free of makeup

•Consider taking arnica montana starting 2 days before treatment if bruising is a concern

•Reschedule if experiencing any active skin infection or inflammation

•Consultation Process:

•Comprehensive facial assessment

•Detailed discussion of concerns and goals

•Review of treatment options and recommendations

•Explanation of expected results and limitations

•Discussion of potential side effects and recovery

•Opportunity to ask questions and address concerns

These preparation steps help ensure optimal treatment outcomes and comfort.

The Treatment Session

The combination treatment experience typically follows this pattern:

•Chemical Brow Lift Component:

•Facial cleansing and preparation

•Precise marking of injection points

•Brief, mild discomfort during injections

•Multiple small injections in specific pattern

•Gentle pressure application after treatment

•Total duration approximately 15-20 minutes

•Under-Eye Component (typically performed separately):

•Facial cleansing and preparation

•Application of topical numbing cream (15-20 minutes)

•Treatment-specific approach (injection, device application, etc.)

•Gentle pressure or cooling as appropriate

•Total duration approximately 30-45 minutes depending on treatment

The entire process is designed for comfort and efficiency, with minimal discomfort and no significant downtime.

Recovery Expectations

Recovery from combination treatments is typically minimal:

•Immediate Post-Treatment:

•Possible tiny injection marks (resolve within hours)

•Potential mild swelling (typically minimal)

•Rare minor bruising (more common with under-eye treatment)

•No activity restrictions for Chemical Brow Lift

•Minimal restrictions for under-eye treatments (avoid extreme heat, exercise for 24 hours)

•First Week:

•Chemical Brow Lift effect begins developing days 3-7

•Under-eye treatments may show immediate effect or gradual improvement

•Any bruising typically resolves within 5-7 days

•Normal activities and makeup application usually possible within 24 hours

•Complete Results:

•Chemical Brow Lift fully developed by days 10-14

•Under-eye treatments show optimal results by 2-4 weeks

•Combined effect continues to refine over first month

•Follow-up assessment at 2-4 weeks for potential refinement

This minimal recovery profile makes combination treatments accessible even for those with busy schedules and public-facing roles.

Results and Maintenance: Sustaining Your Enhanced Appearance

Understanding result longevity and maintenance requirements helps set appropriate expectations.

Expected Outcomes

Combination treatments typically provide these results:

•Visual Improvements:

•More open, alert eye appearance

•Reduced upper eyelid heaviness

•Diminished under-eye hollowing or circles

•Improved skin quality in the periorbital region

•More harmonious transition between eye and cheek

•Overall refreshed, rested appearance

•Emotional and Perceptual Benefits:

•Reduced “tired” or “angry” appearance

•Increased confidence in appearance

•Improved first impression in professional and social contexts

•More accurate reflection of internal emotional state

•Enhanced overall facial harmony

These improvements develop progressively over the first 2-4 weeks following treatment.

Longevity Factors

Result duration varies based on several factors:

Treatment Component	Typical Duration	Influencing Factors
Chemical Brow Lift	3-4 months initially	Muscle strength, metabolism, activity level
Tear Trough Filler	9-18 months	Product used, metabolism, facial movement
Skin Boosters	4-6 months	Skin condition, age, environmental factors
PRP/Exosome Therapy	4-6 months with cumulative effect	Age, skin condition, lifestyle factors
Light Energy Treatments	3-12 months depending on technology	Skin type, concern addressed, maintenance

With regular maintenance, many patients experience extended longevity and cumulative improvement over time.

Optimal Maintenance Schedules

For sustained results, these maintenance schedules are typically recommended:

•Standard Maintenance Protocol:

•Chemical Brow Lift every 3-4 months initially, potentially extending to 4-6 months

•Under-eye treatments every 6-12 months depending on specific approach

•Annual comprehensive reassessment and plan adjustment

•Progressive Enhancement Approach:

•Initial series of treatments at recommended intervals

•Gradual extension of treatment intervals as improvement accumulates

•Potential reduction in treatment intensity over time

•Regular reassessment and protocol adjustment

•Preventative Maintenance Strategy:

•Regular treatments at recommended intervals

•Early intervention approach before concerns become significant

•Comprehensive skincare protocol between treatments

•Lifestyle recommendations to support treatment results

These maintenance approaches can be customized based on individual response, preferences, and goals.

Complementary Treatments: Enhancing Your Results

While the Chemical Brow Lift and under-eye combination creates significant improvement, additional treatments can further enhance results in appropriate cases.

Temple Volume Restoration

Temple hollowing often accompanies eye region aging and affects overall appearance:

•Treatment Approach: Strategic volume replacement in temple hollow

•Complementary Benefit: Provides structural support to lateral brow

•Visual Impact: Creates more harmonious upper face contour

•Technical Synergy: Enhances and extends Chemical Brow Lift effect

•Longevity Advantage: Typically lasts 12-24 months

•Ideal Timing: Often performed with or before Chemical Brow Lift

This complementary treatment addresses the structural foundation supporting the lateral brow, enhancing the overall effect of the Chemical Brow Lift.

Mid-Face Volume Restoration

The mid-face region directly impacts under-eye appearance:

•Treatment Approach: Strategic volume replacement in mid-face and cheek

•Complementary Benefit: Provides structural support to under-eye area

•Visual Impact: Creates smoother transition between under-eye and cheek

•Technical Synergy: Reduces need for direct under-eye treatment

•Longevity Advantage: Typically lasts 12-24 months

•Ideal Timing: Often performed before or with under-eye treatment

By addressing the structural support beneath the under-eye area, this treatment enhances the results of direct under-eye interventions.

Skin Quality Treatments

Overall skin quality significantly impacts eye region appearance:

•Treatment Options: Medical-grade skincare, microneedling, light therapy

•Complementary Benefit: Enhances skin texture, tone, and resilience

•Visual Impact: Creates more refined, luminous appearance

•Technical Synergy: Improves tissue response to other treatments

•Maintenance Value: Extends and enhances professional treatment results

•Ideal Approach: Combination of in-clinic and home care protocols

These treatments address the skin canvas upon which other treatments work, enhancing and extending their benefits.

Full-Face Harmonization

For comprehensive rejuvenation, consider full-face approach:

•Treatment Philosophy: Addressing the face as an integrated whole

•Complementary Benefit: Creates balanced, harmonious rejuvenation

•Visual Impact: Prevents disconnected or unbalanced appearance

•Technical Advantage: Allows comprehensive planning and prioritization

•Efficiency Benefit: Optimizes treatment sequence and combinations

•Personalized Approach: Tailored to individual anatomy and concerns

This holistic approach ensures that eye region enhancement complements and enhances overall facial appearance.

Choosing the Right Provider: Ensuring Optimal Results

The success of combination treatments depends significantly on provider expertise and approach.

Essential Provider Qualifications

When selecting a provider for these sophisticated treatments, look for:

•Specialized Training: Specific education in advanced periorbital treatments

•Technical Expertise: Demonstrated skill in precise injection techniques

•Anatomical Knowledge: Deep understanding of periorbital anatomy

•Aesthetic Judgment: Refined sense of proportion and natural results

•Combination Experience: Specific expertise in coordinating multiple treatments

•Complication Management: Ability to prevent and address potential issues

At Mesglo London, our specialists possess all these qualifications, ensuring optimal safety and results.

The Consultation Process

A thorough consultation should include:

•Comprehensive Assessment: Detailed evaluation of your specific concerns

•Educational Approach: Clear explanation of treatment options and mechanisms

•Realistic Expectations: Honest discussion of potential results and limitations

•Personalized Planning: Customized recommendations based on your needs

•Visual References: Before and after examples of similar cases

•Question Opportunity: Ample time to address all your questions and concerns

This consultation process ensures you make fully informed decisions about your treatment plan.

Red Flags to Avoid

Be cautious of providers who:

•Offer Standardized Approaches: Apply the same treatment to all patients

•Oversell Results: Promise unrealistic outcomes

•Dismiss Concerns: Fail to thoroughly address your questions

•Lack Specialization: Treat the eye region without specific expertise

•Rush Consultation: Don’t take time for thorough assessment

•Pressure Decisions: Don’t allow time for consideration

Avoiding these red flags helps ensure you receive safe, appropriate, and effective treatment.

Conclusion: The Future of Eye Region Rejuvenation

The combination of Chemical Brow Lift with targeted under-eye treatments represents the cutting edge of non-surgical eye rejuvenation. By addressing the entire eye region as a unified aesthetic unit, this approach creates harmonious, natural-looking results that exceed what either treatment can achieve independently.

At Mesglo London, our Marylebone specialists continue to refine and advance these combination techniques, developing innovative protocols that maximize synergy while maintaining natural movement and expression. Through sophisticated approaches like the Orbital Frame Technique, the Progressive Enhancement Protocol, and the Regenerative Combination, we create customized treatment plans that address each patient’s unique concerns and goals.

The ideal outcome—looking like yourself at your best rather than looking “treated”—is particularly achievable through these combination approaches. By balancing muscle modulation with structural support and skin quality enhancement, we help patients present their most refreshed, alert appearance in both professional and personal contexts.

To explore how a customized combination of Chemical Brow Lift and under-eye treatments might benefit you, contact us to schedule a consultation at our Marylebone clinic.

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