Hair thinning, excessive shedding, and slow regrowth can be frustrating, affecting both confidence and overall appearance. While PRP (Platelet-Rich Plasma) and exosomes for hair have been widely used for hair restoration, a groundbreaking new solution is emerging: polynucleotides—a powerful regenerative treatment that repairs hair follicles, extends the growth cycle, and revitalises scalp health.
So, how do polynucleotides work for hair restoration, and how do they compare to PRP and exosomes? In this guide, we explore why polynucleotides for hair loss are becoming the hidden secret to stronger, healthier hair.
What Are Polynucleotides & How Do They Stimulate Hair Growth?
Polynucleotides (PNs) are biomolecules derived from DNA fragments that have been extensively studied for their ability to repair and regenerate tissues. When applied to the scalp, polynucleotides work by:
🔬 Stimulating Hair Follicle Repair – Polynucleotides activate stem cells and fibroblasts, promoting the regeneration of weakened or damaged hair follicles.
💧 Enhancing Scalp Hydration & Circulation – By improving blood flow and hydration levels, polynucleotides create the ideal environment for healthy hair growth.
⚡ Extending the Anagen (Growth) Phase – Polynucleotides prolong the active hair growth phase, reducing excessive shedding and accelerating new hair development.
🌿 Reducing Scalp Inflammation – Chronic inflammation and oxidative stress contribute to hair loss; polynucleotides counteract these effects, calming the scalp and preventing follicle damage.
Unlike traditional treatments that only stimulate hair growth, polynucleotides work at a deep cellular level, repairing and fortifying the entire hair ecosystem for long-term results.
Polynucleotides vs. PRP vs. Exosomes: Which Works Best for Hair Regrowth?
While PRP (Platelet-Rich Plasma) and exosomes have been widely used in hair restoration, polynucleotides offer unique advantages that set them apart.
| Feature | Polynucleotides (PNs) | PRP (Platelet-Rich Plasma) | Exosomes |
|---|---|---|---|
| Mechanism | Tissue regeneration & follicle repair | Growth factor stimulation | Cellular communication & signalling |
| Longevity | Long-lasting results, gradual improvement | Requires frequent top-ups | Potentially long-lasting but expensive |
| Scalp Inflammation Reduction | Strong anti-inflammatory properties | Can cause mild inflammation | Anti-inflammatory effects but variable |
| Suitability | Ideal for thinning hair, weak follicles, & scalp repair | Best for early-stage hair loss | Best for advanced hair loss cases |
Key Takeaways:
- PRP is effective for stimulating weak hair follicles but requires regular treatments.
- Exosomes deliver potent growth factors but are costly and still under clinical evaluation.
- Polynucleotides stand out as a comprehensive solution, healing and repairing the scalp while prolonging hair growth.
How Do Polynucleotides Improve Scalp Health?
A healthy scalp is essential for stronger, thicker hair, and polynucleotides target key factors that influence hair loss:
🩸 Increases Scalp Blood Flow: Improves oxygen and nutrient supply to hair follicles, boosting hair strength.
💆 Balances Sebum Production: Helps control excess oiliness or dryness, creating an optimal scalp environment.
🔥 Reduces Chronic Inflammation: Calms scalp irritation caused by stress, pollution, and hair treatments.
🦠 Supports Scalp Microbiome: Encourages healthy bacteria on the scalp, preventing dandruff and itchiness.
By treating both the scalp and hair follicles, polynucleotides stop hair loss at its root cause, making them a powerful option for long-term hair restoration.
What Results Can You Expect? Before & After Case Studies
Many patients see noticeable improvements within 3 months, with continued enhancement over time.
Before & After Transformations:
🖼 Before: Visible hair thinning, excess shedding, and weak follicle growth.
🖼 After: Thicker, stronger hair with increased density and reduced shedding.
Results Timeline:
- 1 Month: Reduced hair shedding, scalp feels healthier.
- 3 Months: Visible thickening of hair, baby hairs start emerging.
- 6+ Months: Fuller, denser hair with improved quality and strength.
How Many Sessions Are Needed?
Most patients require 3 to 5 sessions, spaced 2 to 4 weeks apart, depending on the severity of hair loss.
- Mild Hair Thinning: 3 sessions for scalp rejuvenation and follicle repair.
- Moderate Hair Loss: 4–5 sessions to stimulate regrowth and extend the hair cycle.
- Severe Hair Loss: May require additional maintenance treatments over time.
Is Polynucleotide Hair Restoration Safe?
Yes! Polynucleotide therapy is minimally invasive and highly biocompatible, meaning it works naturally with your body. It has been extensively studied for its regenerative properties, and side effects are rare.
🔹 Minimal Downtime: Mild redness or sensitivity for 24–48 hours.
🔹 No Risk of Overgrowth: Unlike fillers or aggressive treatments, polynucleotides work gradually and naturally.
🔹 Safe for All Hair Types: Suitable for men and women with all hair textures.
Why Choose Mesglo London for Polynucleotide Hair Regeneration?
At Mesglo Aesthetic Clinic London, we specialise in cutting-edge hair restoration treatments backed by science and performed by expert practitioners. Our polynucleotide-based hair therapy is tailored to your unique hair concerns, ensuring maximum results with minimal downtime.
🌟 Advanced regenerative treatments for optimal hair and scalp health.
🌟 Highly experienced practitioners trained in hair loss solutions.
🌟 State-of-the-art clinic providing the latest non-surgical innovations.
Book Your Polynucleotide Hair Consultation Today
If you’re looking for a powerful, natural solution to restore your hair and scalp, book a consultation at Mesglo London today. Our team will create a personalised treatment plan to help you achieve thicker, healthier, and stronger hair.
📍 Mesglo Aesthetic Clinic London
Unit 4, 10 Portman Square, London W1H 6AZ, United Kingdom
🌍 https://mesglolondon.co.uk/
📅 Schedule your appointment now and start your journey to fuller hair!