Cosmelan Peel Treatment Marylebone, London
Target Pigmentation at Its Source with Advanced Cosmelan Depigmentation Therapy
The Cosmelan Peel is one of the most powerful professional depigmentation treatments available today. Unlike standard chemical peels that only work on the surface, Cosmelan targets pigmentation at its root — within the melanocytes responsible for excess melanin production.
At Mesglo Aesthetic Clinic in Marylebone, our practitioners use the Cosmelan method to visibly reduce melasma, post-inflammatory hyperpigmentation, sun damage, and uneven tone, while restoring a clearer, more even complexion with minimal risk and downtime.
Raheena is friendly, professional, and knowledgeable. She made me feel comfortable, listened to what I wanted, and gave me great advice. The treatment was smooth, and I love the results. Highly recommend!
Cosmelan Peel Treatment Before and After



TREATMENT OVERVIEW
Treatment Areas:
- Full face
- Neck and décolletage (optional)
- Hands (optional add-on)
Procedure Time: 45–60 minutes (in-clinic mask application)
Anaesthesia: None required
Downtime: 3–7 days of mild peeling and redness
Results Visible: Within 2–3 weeks, continuing to improve for up to 8 weeks
Results Last: 6–12 months with proper skincare and SPF protection
Recommended Sessions: One professional treatment with dedicated home-care protocol
COSMELAN PEEL PRICE FROM £1,800
Why Choose the Cosmelan Peel?
Pigmentation is among the most difficult skin concerns to treat effectively. It can be hormonal, genetic, or environmental — and often resistant to topical skincare. The Cosmelan Professional System works through a dual-action process that both corrects existing discolouration and regulates melanin production to prevent future recurrence.
Key Benefits
Works on all skin tones and types
Reduces visible melasma and hyperpigmentation
Brightens dull, uneven complexions
Helps manage acne-related pigmentation
Smooths and refines overall skin texture
Minimal risk, medically supervised treatment

The Science Behind Cosmelan
The Cosmelan Peel combines potent depigmenting agents — including azelaic acid, kojic acid, arbutin, and phytic acid — in a unique medical-grade formula that inhibits tyrosinase, the key enzyme involved in melanin synthesis.
At Mesglo, this process is tailored to your individual pigmentation pattern. Our clinicians perform a detailed skin assessment before beginning treatment, ensuring your plan is both safe and effective. The Cosmelan system unfolds in two carefully timed phases:
Professional Application (In Clinic)
A thick depigmenting mask is applied and remains on the skin for a prescribed number of hours depending on your skin tone and condition.Home Maintenance Phase (At Home)
After removal, you’ll continue a dedicated home care routine using the Cosmelan maintenance products to reinforce the results and control melanin activity long-term.
This multi-phase approach allows pigmentation to fade progressively, while improving luminosity, texture, and hydration.
Results and Recovery
You’ll begin to notice visible brightening and reduced pigmentation within 2 to 3 weeks, with continued improvement over 4 to 8 weeks. Some mild peeling and redness may occur — a normal part of the skin renewal process.
Once complete, the skin appears clearer, more even, and radiant, often with a visible reduction in melasma and sun-induced pigmentation by up to 90%.
Results are long-lasting when combined with strict UV protection and home maintenance, and many clients report a complete transformation in their skin confidence.
Who Is It For?
The Cosmelan Peel is suitable for most skin types and tones, including sensitive and darker complexions. It is ideal if you experience:
Melasma or chloasma
Post-acne or post-inflammatory pigmentation
Uneven tone or dark patches
Sun spots and age-related pigmentation
General dullness or texture irregularities
Your Mesglo practitioner will always assess your skin in detail before recommending treatment, ensuring it’s the most appropriate and safe option for your concerns.
What to Expect at Mesglo, Marylebone
At Mesglo Aesthetic Clinic, we are known for natural, healthy-looking skin transformations and for our five-star approach to patient care. Every Cosmelan treatment is delivered by trained medical professionals in a calm, discreet Marylebone setting designed for comfort and precision.
You’ll receive:
A comprehensive consultation and skin analysis
Personalised Cosmelan protocol planning
Professional application and aftercare guidance
Full follow-up support to monitor progress
We pride ourselves on results that look refined, balanced, and authentically radiant — never artificial.
Aftercare and Longevity
Post-treatment care is essential. You’ll be guided through a structured home routine to maintain your results and prevent pigment reactivation. Daily SPF protection is non-negotiable — our clinicians will recommend a medical-grade sunscreen and antioxidant routine to preserve clarity.
With consistent maintenance, your results can last for many months, helping your complexion remain bright, even, and resilient.
Why Choose Mesglo for Your Cosmelan Peel in London
Located in the heart of Marylebone, London, Mesglo Aesthetic Clinic is fast becoming one of the most trusted and reviewed aesthetic clinics in the city.
Our practitioners combine advanced training, medical-grade products, and a philosophy of subtle enhancement to deliver visible yet natural outcomes.
Every treatment is tailored to your unique skin biology, ensuring you achieve a smoother, brighter, and more confident complexion safely and effectively.
Frequently Asked Questions
What exactly does the Cosmelan Peel do?
The Cosmelan Peel is a professional depigmentation system designed to correct and regulate excess melanin production. It not only fades visible pigmentation such as melasma and sun spots, but also prevents new patches from forming by calming overactive melanocytes beneath the skin’s surface.
How is the Cosmelan Peel different from a chemical peel?
Unlike a standard chemical peel that exfoliates the top layer of skin, the Cosmelan Peel works much deeper. It actively reduces melanin activity at a cellular level, addressing the cause of pigmentation rather than simply resurfacing the skin. This makes it far more effective for melasma and long-term pigment control.
Who is suitable for the Cosmelan treatment?
The Cosmelan Peel is suitable for most skin types and tones, including darker complexions that may not tolerate traditional peels. It’s particularly recommended for those experiencing melasma, post-acne pigmentation, sun damage, or general uneven skin tone. A consultation at Mesglo Aesthetic Clinic in Marylebone ensures it’s right for your skin.
Is the Cosmelan Peel painful?
The treatment is generally well-tolerated. You may experience mild tingling or warmth during application, followed by tightness or peeling in the days after. This is completely normal and indicates that the formula is actively renewing the skin.
What should I expect after treatment?
In the first week, you may notice redness and light peeling as the skin renews. From week two onwards, the complexion becomes visibly brighter, smoother, and more even. Full results typically develop within six to eight weeks when the home-care phase is followed consistently.
How long do the results last?
Results can last between 6–12 months with the right aftercare and consistent sun protection. Mesglo specialists often recommend maintenance with the Cosmelan 2 cream and a daily SPF to prolong and stabilise the results.
Can the Cosmelan Peel be done on darker skin?
Yes — it’s one of the few medical-grade pigmentation treatments proven safe and effective for darker skin tones. Our Mesglo practitioners always perform a detailed skin analysis to tailor the protocol and minimise sensitivity.
What is the downtime like?
Expect 3–7 days of mild peeling, redness, or tightness. These effects are temporary and manageable with your post-care kit. You can usually return to normal activities after a few days, though strict sun protection is essential.
How soon will I see results?
Most clients see visible improvement within 2–3 weeks, with progressive lightening and refinement continuing for up to 8 weeks. Skin appears clearer, smoother, and more radiant with each passing week.
Can I wear makeup after the Cosmelan Peel?
You’ll need to avoid makeup for the first few days to allow the skin to heal. Once peeling subsides, you can return to mineral-based makeup if needed — though many clients find they need less coverage after treatment.
Is the Cosmelan Peel safe during pregnancy or breastfeeding?
The treatment is not recommended during pregnancy or breastfeeding, as hormonal fluctuations may affect pigment response and sensitivity. It’s best to wait until your hormones have stabilised before undergoing any depigmentation procedure.
What is included in the Cosmelan treatment cost?
At Mesglo, the £1,800 fee covers your full in-clinic treatment, the medical-grade aftercare kit, and all follow-up appointments to monitor your progress and results.
Will pigmentation return after the Cosmelan Peel?
Without proper aftercare and UV protection, pigmentation can reappear over time. However, regular maintenance and professional skincare guidance at Mesglo help ensure your skin stays clear, balanced, and luminous long-term.
How should I prepare before a Cosmelan Peel?
Avoid active skincare ingredients such as retinol, AHAs, or BHAs for at least one week prior to your treatment. Your Mesglo practitioner will provide a personalised pre-treatment plan to optimise your skin for best results.
Why choose Mesglo in Marylebone for your Cosmelan Peel?
Mesglo Aesthetic Clinic combines advanced clinical expertise with a reputation for natural, refined results. Located in central Marylebone, the clinic has earned all 5-star reviews for its personalised care and precision-driven approach to pigmentation treatments.
Book Your Consultation for Cosmelan Peel at our clinic in Marylebone, London
Your journey to luminous, even-toned skin begins with an expert consultation.
Experience why Mesglo has become London’s go-to clinic for the Cosmelan Peel and advanced pigmentation treatments.
📍 Clinic Location:
Mesglo Aesthetic Clinic Marylebone London, Unit 4, 10 Portman Square, London, W1H 6AZ
📞 Call Us: 07830402077
📅 Contact Us: info@mesglolondon.co.uk