Polynucleotide for Face in London
Deep Skin Regeneration, Hydration & Lifting
Polynucleotide therapy is an advanced, scientifically backed skin bio-stimulation treatment that rejuvenates, hydrates, and strengthens the skin at a cellular level. Using highly purified polynucleotides derived from Salmon DNA, this treatment stimulates collagen and elastin production, offering a powerful lifting and hydrating effect without altering facial features. At Mesglo London, we provide expert polynucleotide facial treatments to restore skin health, combat ageing, and enhance skin firmness with minimal downtime.
Polynucleotide Treatment Results

Treatment Overview
📍 Treatment Areas:
- Face
- Neck
- Décolletage
⏳ Procedure Time: 30–45 minutes
💉 Anaesthesia: Optional numbing cream
⏱️ Downtime: Minimal (mild swelling or redness may last up to 48 hours)
📆 Results Last: 6–12 months
🔄 Recommended Sessions: 4–6 sessions spaced 2–4 weeks apart for best results
Polynucleotide Treatment Price From £350
What are Polynucleotides & How Do They Work?
Polynucleotides are biological molecules extracted from purified Salmon DNA, known for their ability to stimulate skin renewal and regeneration. This treatment works through a three-tiered rejuvenation process:
✔ Lifting & Tightening – Polynucleotides activate fibroblast receptors, increasing collagen and elastin production, leading to firmer, thicker, and smoother skin.
✔ Antioxidant Power – Polynucleotides neutralise free radicals, reducing oxidative stress and preventing premature ageing.
✔ Deep Hydration – Polynucleotides bind water within the skin, providing long-lasting hydration and a youthful glow.
This multi-action approach ensures deep tissue repair, hydration, and long-term skin strengthening, making it one of the most advanced skin bio-stimulation treatments available.
✔ 100% biocompatible & natural
✔ Targets sagging, fine lines & dull skin
✔ Rejuvenates without altering facial features
Benefits of Polynucleotide Facial Therapy
✅ Lifts & Firms the Skin – Stimulates collagen & elastin production for a more youthful, sculpted look
✅ Deep Hydration – Provides long-lasting moisture, leaving skin plump and radiant
✅ Reduces Wrinkles & Fine Lines – Strengthens the skin barrier for smoother texture
✅ Enhances Skin Elasticity – Improves skin tightness & resilience
✅ Antioxidant Protection – Neutralises free radicals, preventing skin ageing & damage
✅ Safe for All Skin Types – 100% biocompatible, natural & free from sensitising agents

What Skin Concerns Can Polynucleotides Address?
- ✔ Loss of firmness & elasticity – Lifts sagging areas for tighter skin
✔ Fine lines & wrinkles – Stimulates collagen for smoother texture
✔ Dehydrated, dull skin – Provides long-lasting moisture & glow
✔ Uneven skin tone – Enhances radiance & skin renewal
✔ Thin, fragile skin – Strengthens the skin barrier for improved resilience
What to Expect During Your Appointment
Consultation
A skin assessment to determine your unique needs and treatment plan.
Procedure
- 10 precise injection points are targeted for maximum skin stimulation.
- Polynucleotides are gently injected into the skin to begin the rejuvenation process.
- The procedure takes 30–45 minutes with minimal discomfort.
Aftercare & Results
✔ Expect minor redness, swelling, or bruising, which resolves within 48 hours.
✔ Avoid intense heat, sun exposure, and heavy makeup for 24 hours.
✔ Visible improvements begin in 2–3 weeks, with full results developing over 3 months.
✔ A series of 4–6 treatments spaced 2–4 weeks apart is recommended for best results.
Who is This Treatment For?
✔ Individuals with ageing, sagging, or dehydrated skin
✔ Those wanting a natural approach to skin rejuvenation
✔ Clients looking for deep skin hydration & antioxidant protection
✔ Anyone seeking non-surgical skin tightening & bio-stimulation
This treatment is suitable for all skin types & ages, offering a natural, long-term skin restoration solution.
Frequently Asked Questions
How are polynucleotides different from traditional dermal fillers?
Unlike fillers that add volume, polynucleotides stimulate natural collagen and elastin production, strengthening and rejuvenating the skin over time.
How long does it take to see results?
Initial hydration and glow appear within 2–3 weeks, with full skin lifting and firming results in 3 months.
How long do results last?
Results typically last 6–12 months, with maintenance treatments every 3–4 months recommended.
Is the procedure painful?
Most clients report minimal discomfort, as fine needles are used. A numbing cream can be applied for extra comfort.
Can I combine this treatment with other aesthetic procedures?
Yes! Polynucleotides can be paired with microneedling, exosomes, PRP, or laser treatments to boost results.
Are polynucleotides safe?
Yes, polynucleotides are biocompatible, meaning they are well-tolerated and safe for all skin types.
Will my face look different or unnatural?
Not at all! Polynucleotides work with your natural skin biology, restoring your skin’s strength and hydration without altering facial features.
Book Your Polynucleotide Facial Consultation Today
Transform your skin with polynucleotide therapy at Mesglo London. Achieve firmer, smoother, and deeply hydrated skin with scientifically advanced bio-stimulation.
📍 Clinic Location:
Mesglo Aesthetic Clinic London, Unit 4, 10 Portman Square, London, W1H 6AZ
📞 Call Us: 07830402077
📅 Contact Us: info@mesglolondon.co.uk