Mesglo London

Polynucleotide for Face in London

Deep Skin Regeneration, Hydration & Lifting

Polynucleotide therapy is an advanced, scientifically backed skin bio-stimulation treatment that rejuvenates, hydrates, and strengthens the skin at a cellular level. Using highly purified polynucleotides derived from Salmon DNA, this treatment stimulates collagen and elastin production, offering a powerful lifting and hydrating effect without altering facial features. At Mesglo London, we provide expert polynucleotide facial treatments to restore skin health, combat ageing, and enhance skin firmness with minimal downtime.

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08:16 27 Apr 25
Excellent service! Rahena was very friendly and attentive to my needs. Results to my treatment were amazing! Highly recommend!
ALV UjX2dQhY3 9TmF1P7CIJcBlQiRw9iN1hOZymFv5g96cjSlay6WK =s120 c rp mo br100Alice Hankin
18:50 14 Apr 25
Rahena consistently provides a premium service - my lashes and brows always look immaculate afterwards and the tint lasts for weeks. Highly recommend!
ACg8ocIMtIEJ92WCfxf50zdE2DojVEOhuHPXfSBe14bshmShHxpvhA=s120 c rp mo br100Rabina Khanam
15:58 02 Apr 25
I had a chemical brow lift treatment at Mesglo London, and the entire experience from consultation to treatment was a perfect 10/10. Rahena is incredibly professional and knowledgeable, making me feel completely at ease. I’d definitely recommend Mesglo London to anyone!
ACg8ocJTiwCrToPEjO3zEZECu 6bIkrDYuHmsBBXtjNLRULw7K R5w=s120 c rp mo br100Abdul Bari
14:14 02 Apr 25
Had an amazing experience with my Exosome treatment! Rahena provided an excellent service, and the treatment itself was amazing. I’m already seeing great results and couldn’t be happier. Highly recommend!
ACg8ocL4D1kvfi6zfnImFugPRrcE5JLypPylVeCir ePxufTaoTzDw=s120 c rp mo br100Adam Mufasa
11:45 02 Apr 25
Amazing Service!Raheena is friendly, professional, and knowledgeable. She made me feel comfortable, listened to what I wanted, and gave me great advice. The treatment was smooth, and I love the results. Highly recommend!
ALV UjWs3PyIKcaguexuAcUPaJ5ey9uJNy0d9qFmXoqaHwMxaY0EYrdR=s120 c rp mo br100Carla Edwards
11:16 02 Apr 25
I experienced such great service, felt understood and most of all have had a great outcome after having Exosomes. I will definitely come back, wouldn’t think of going anywhere else. Thank you Raheena you have definitely made my skin glow
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09:36 02 Apr 25
I had my Botox with miss Rahena and it was the best Botox I have had. It has lasted so long and I will definitely be booking in for more treatments with her. I highly recommend her and her practice.
ACg8ocLaHamCJsmuBBIhlSy0xXbwU27vSCzyovHWNy66AqteRz5 LQ=s120 c rp mo br100Emily Hankin
14:23 31 Mar 25
I would recommend Rahena for everything! Amazing service and results are perfect.
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06:54 29 Mar 25
I had an amazing experience! Rahina was incredibly friendly, and the treatment was great. I felt genuinely cared for throughout my visit. Can’t wait for my next session
ALV UjXFVSgXfy0wquuF9g8Tn5YDf6f88yIcZEgA663zdR8bwH4hKg=s120 c rp mo br100Nina Singh
19:13 28 Mar 25
I had an amazing experience! Rahena was incredibly friendly, and the treatment was great. I felt genuinely cared for throughout my visit. Can’t wait for my next session
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Polynucleotide Treatment Results

Treatment Overview

📍 Treatment Areas:

  • Face
  • Neck
  • Décolletage

Procedure Time: 30–45 minutes
💉 Anaesthesia: Optional numbing cream
⏱️ Downtime: Minimal (mild swelling or redness may last up to 48 hours)
📆 Results Last: 6–12 months
🔄 Recommended Sessions: 4–6 sessions spaced 2–4 weeks apart for best results

Polynucleotide Treatment Price From £350

What are Polynucleotides & How Do They Work?

Polynucleotides are biological molecules extracted from purified Salmon DNA, known for their ability to stimulate skin renewal and regeneration. This treatment works through a three-tiered rejuvenation process:

Lifting & Tightening – Polynucleotides activate fibroblast receptors, increasing collagen and elastin production, leading to firmer, thicker, and smoother skin.
Antioxidant Power – Polynucleotides neutralise free radicals, reducing oxidative stress and preventing premature ageing.
Deep Hydration – Polynucleotides bind water within the skin, providing long-lasting hydration and a youthful glow.

This multi-action approach ensures deep tissue repair, hydration, and long-term skin strengthening, making it one of the most advanced skin bio-stimulation treatments available.

100% biocompatible & natural
Targets sagging, fine lines & dull skin
Rejuvenates without altering facial features

Benefits of Polynucleotide Facial Therapy

Lifts & Firms the Skin – Stimulates collagen & elastin production for a more youthful, sculpted look
Deep Hydration – Provides long-lasting moisture, leaving skin plump and radiant
Reduces Wrinkles & Fine Lines – Strengthens the skin barrier for smoother texture
Enhances Skin Elasticity – Improves skin tightness & resilience
Antioxidant Protection – Neutralises free radicals, preventing skin ageing & damage
Safe for All Skin Types – 100% biocompatible, natural & free from sensitising agents

Client after polynucleotide tratment
  • Loss of firmness & elasticity – Lifts sagging areas for tighter skin
    Fine lines & wrinkles – Stimulates collagen for smoother texture
    Dehydrated, dull skin – Provides long-lasting moisture & glow
    Uneven skin tone – Enhances radiance & skin renewal
    Thin, fragile skin – Strengthens the skin barrier for improved resilience

Consultation

A skin assessment to determine your unique needs and treatment plan.

Procedure

  • 10 precise injection points are targeted for maximum skin stimulation.
  • Polynucleotides are gently injected into the skin to begin the rejuvenation process.
  • The procedure takes 30–45 minutes with minimal discomfort.

Aftercare & Results

✔ Expect minor redness, swelling, or bruising, which resolves within 48 hours.
✔ Avoid intense heat, sun exposure, and heavy makeup for 24 hours.
Visible improvements begin in 2–3 weeks, with full results developing over 3 months.
✔ A series of 4–6 treatments spaced 2–4 weeks apart is recommended for best results.

✔ Individuals with ageing, sagging, or dehydrated skin
✔ Those wanting a natural approach to skin rejuvenation
✔ Clients looking for deep skin hydration & antioxidant protection
✔ Anyone seeking non-surgical skin tightening & bio-stimulation

This treatment is suitable for all skin types & ages, offering a natural, long-term skin restoration solution.

Frequently Asked Questions

Unlike fillers that add volume, polynucleotides stimulate natural collagen and elastin production, strengthening and rejuvenating the skin over time.

Initial hydration and glow appear within 2–3 weeks, with full skin lifting and firming results in 3 months.

Results typically last 6–12 months, with maintenance treatments every 3–4 months recommended.

Most clients report minimal discomfort, as fine needles are used. A numbing cream can be applied for extra comfort.

Yes! Polynucleotides can be paired with microneedling, exosomes, PRP, or laser treatments to boost results.

Yes, polynucleotides are biocompatible, meaning they are well-tolerated and safe for all skin types.

Not at all! Polynucleotides work with your natural skin biology, restoring your skin’s strength and hydration without altering facial features.

Book Your Polynucleotide Facial Consultation Today

Transform your skin with polynucleotide therapy at Mesglo London. Achieve firmer, smoother, and deeply hydrated skin with scientifically advanced bio-stimulation.

📍 Clinic Location:

Mesglo Aesthetic Clinic London, Unit 4, 10 Portman Square, London, W1H 6AZ

📞 Call Us: 07830402077

📅 Contact Us: info@mesglolondon.co.uk