
Polynucleotide Face Therapy London
DNA-Based Skin Regeneration in Marylebone

What is Polynucleotide Face?
Polynucleotide therapy utilises purified DNA fragments to stimulate your skin's natural regenerative processes. This innovative treatment promotes fibroblast activity, enhances collagen and elastin production, and provides deep hydration at the cellular level.
Polynucleotide therapy represents one of the most exciting advances in regenerative aesthetics, offering a scientifically-proven approach to skin rejuvenation that harnesses the power of DNA. At Mesglo London, we specialise in this cutting-edge treatment that delivers remarkable results through genuine tissue regeneration.
Polynucleotides are chains of nucleotides derived from highly purified salmon DNA. When injected into the skin, they stimulate fibroblast activity, the cells responsible for producing collagen and elastin. This results in improved skin structure, enhanced hydration, and a natural lifting and firming effect.
Key Benefits
- Stimulates fibroblast activity for natural regeneration
- Boosts collagen and elastin production
- Provides deep cellular hydration
- Improves skin elasticity and firmness
- Reduces visible signs of ageing
- Delivers natural-looking, lasting results
- Suitable for face, neck, and décolletage
- Minimal downtime required
Treatment Process
- Assessment Detailed skin assessment and treatment planning
- Numbing Application of topical anaesthetic for comfort
- Injection Strategic placement of polynucleotide solution
- Distribution Even distribution technique for optimal results
- Soothing Post-treatment soothing and cooling
- Guidance Comprehensive aftercare instructions
Questions people ask
What are polynucleotides and how do they rejuvenate skin?
Polynucleotides are chains of nucleotides derived from salmon DNA. They stimulate tissue regeneration, improve skin hydration, and promote the production of collagen and elastin, resulting in firmer, more youthful-looking skin.
How long do polynucleotide treatment results last?
Results typically last 6-12 months, with many clients experiencing ongoing improvement. Regular maintenance treatments help sustain and build upon initial improvements for cumulative benefits.
Can polynucleotides be combined with other treatments?
Yes, polynucleotides work excellently alongside other treatments like exosomes, dermal fillers, and skin boosters for comprehensive facial rejuvenation. We can create a bespoke treatment plan combining multiple approaches.
Real results from this treatment
Photographs of real Mesglo clients, shown with their permission. Results vary from person to person.

“The clinic has such a luxurious feel and the treatments are top-notch. Rahena really takes the time to understand what you want and delivers beyond expectations.”Read all reviews
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Start with a conversation
A consultation at 4 Baker Street comes first in every case. Rahena assesses your skin or hair, explains what would and would not help, and there is no obligation to go ahead.



