Pigmentation Treatment London | Marylebone Clinic

Pigmentation, including melasma, post-inflammatory hyperpigmentation (PIH), sun spots, and uneven skin tone, is one of the most common skin concerns we treat at Mesglo Aesthetic Clinic Marylebone, London. Our practitioners assess the type, depth, and cause of your pigmentation before recommending the most appropriate clinical treatment.

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Waiting area at Mesglo London, Marylebone

What Causes Pigmentation?

Pigmentation occurs when melanocytes produce excess melanin in response to triggers including UV exposure, hormonal changes (particularly during pregnancy or with oral contraceptive use), post-acne inflammation, and skin injury. Melasma is the most complex form, often requiring a multi-modal treatment approach to achieve lasting results.

What We Offer

We offer a curated range of clinically proven pigmentation treatments, each selected for their evidence base and suitability across Fitzpatrick skin types I to VI:

Cosmelan Peel

gold-standard depigmentation system for melasma and stubborn pigmentation

Messenger Peel

regenerative chemical peel for PIH, acne marks, and skin renewal

Microneedling

collagen induction therapy for post-inflammatory pigmentation and texture

Mesotherapy

brightening vitamin cocktails targeting uneven skin tone

Chemical Peels

glycolic, lactic, and TCA peels for surface-level brightening

Frequently Asked Questions

What results can I expect?

Results depend on the type and depth of pigmentation. Cosmelan Peel typically delivers 70 to 90% reduction in melasma within 8 weeks. Messenger Peel shows visible improvement from session 1. Microneedling protocols for PIH generally require 3 to 6 sessions spaced 4 weeks apart. Our practitioners will set realistic expectations at your initial consultation.

Is pigmentation treatment safe for darker skin tones?

Yes. Our practitioners are experienced in treating all Fitzpatrick skin types, including types IV to VI. We select treatments and protocols specifically calibrated for darker skin tones to minimise the risk of post-treatment hyperpigmentation. The Cosmelan Peel and Messenger Peel are both validated for use across all skin types.

5.030 Google reviews
“I finally found a clinic that delivers results I actually love. The attention to detail and personalised approach made all the difference. My skin has never looked better.”
Victoria S., December 2025
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A consultation at 4 Baker Street comes first in every case. Rahena assesses your skin or hair, explains what would and would not help, and there is no obligation to go ahead.

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