A NAD+ shot is an intramuscular (IM) injection of Nicotinamide Adenine Dinucleotide — a coenzyme found in every cell of the body. NAD+ plays a central role in energy metabolism, DNA repair, and cellular regeneration. Levels decline with age, and IM injections provide a direct, efficient way to replenish them.

What are the benefits of NAD+ injections?

NAD+ injections can support increased energy levels, improved mental clarity and focus, enhanced cellular repair and anti-ageing processes, better metabolic function, and support for overall wellbeing. Many clients report feeling more energised within days of treatment.

How much does a NAD+ shot cost at Mesglo London?

NAD+ shots at Mesglo London start from £300 per session. Package pricing is available for courses of 4 or more sessions. Please contact us or book a consultation for a personalised quote.

NAD+ Shots London - Intramuscular Injection Marylebone

Q: Is a NAD+ injection painful?

NAD+ IM injections are administered into the muscle (typically the deltoid or gluteal muscle) and cause minimal discomfort — similar to a standard vaccination. The procedure takes less than 5 minutes.

NAD+ (Nicotinamide Adenine Dinucleotide) is one of the most important coenzymes in the human body — essential for energy production, DNA repair, and cellular regeneration. At Mesglo Aesthetic Clinic Marylebone, London, we offer professional NAD+ intramuscular (IM) injections to help replenish declining NAD+ levels, supporting energy, cognitive function, and healthy ageing from within.

Price: From £300 per session | Duration: 5–10 minutes | Results: Progressive energy and wellbeing improvement

What is NAD+?

NAD+ is a coenzyme found in every living cell, playing a critical role in converting nutrients into cellular energy (ATP), activating sirtuins (longevity proteins), repairing damaged DNA, and regulating circadian rhythms. Levels of NAD+ decline significantly with age — by the time we reach 50, NAD+ levels can be up to 50% lower than in youth. This decline is associated with reduced energy, slower cellular repair, and increased susceptibility to age-related conditions.

Intramuscular injection delivers NAD+ directly into the bloodstream via muscle tissue, bypassing the digestive system for maximum bioavailability and faster onset compared to oral supplements.

Benefits of NAD+ Shots

Increased cellular energy and reduced fatigue
Enhanced mental clarity, focus, and cognitive function
Support for DNA repair and cellular regeneration
Anti-ageing effects at the cellular level
Improved metabolic function and weight management support
Support for muscle recovery and physical performance
Potential mood and sleep quality improvements

Who is NAD+ Suitable For?

NAD+ injections are suitable for adults looking to support healthy ageing, combat fatigue, enhance cognitive performance, or complement an existing wellness routine. They are particularly popular with those experiencing low energy, brain fog, or the effects of a demanding lifestyle. A brief health consultation is conducted before treatment to ensure suitability.

The Treatment Process

Brief health consultation and suitability assessment
Preparation of the NAD+ injection
Intramuscular injection (typically into the deltoid or gluteal muscle)
Post-injection observation (5 minutes)
Aftercare guidance and follow-up protocol

Frequently Asked Questions

What is a NAD+ shot?

A NAD+ shot is an intramuscular injection of Nicotinamide Adenine Dinucleotide, a coenzyme essential for energy metabolism, DNA repair, and cellular regeneration. IM injection provides direct, efficient delivery with high bioavailability.

How often should I have NAD+ shots?

We typically recommend an initial course of 4 weekly sessions, followed by monthly maintenance injections. Your practitioner will personalise the protocol based on your health goals.

Is a NAD+ injection painful?

NAD+ IM injections cause minimal discomfort — similar to a standard vaccination. The procedure takes less than 5 minutes with no downtime.

Book your NAD+ shot at Mesglo London, Marylebone. You may also be interested in our B12 injections or mesotherapy skin treatments.

Visit Our Marylebone Clinic

Mesglo London is located in the heart of Marylebone, W1H, London. Our clinic is easily accessible from Baker Street, Bond Street, and Regent's Park Underground stations.

View Mesglo London on Google Maps for directions, opening hours, and patient reviews.

Compare NAD+ Shots with Other Treatments

Not sure if NAD+ shots are right for you? Use our interactive comparison tool to explore all treatments at Mesglo London side by side.

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