What is Profhilo and how is it different from dermal fillers?

Profhilo is a bio-remodelling injectable containing one of the highest concentrations of hyaluronic acid available (64mg per 2ml). Unlike dermal fillers, Profhilo does not add volume or change facial structure. Instead, it disperses beneath the skin to provide deep hydration and stimulate four types of collagen and elastin, remodelling and tightening the skin from within.

Where can Profhilo be used on the body?

Profhilo is most commonly used on the face and neck, but it is also highly effective for the hands, decolletage, arms, and abdomen. It is particularly beneficial for areas showing skin laxity, crepiness, or dehydration that are difficult to address with other treatments.

Is Profhilo suitable for younger patients?

Yes, Profhilo is suitable for adults of all ages. Younger patients in their 30s often use it as a preventative treatment to maintain skin quality and hydration. It is particularly popular with those who want to improve skin texture and glow without adding volume or altering their natural appearance.

What is the downtime after Profhilo?

Profhilo has minimal downtime. You may experience small injection site bumps that resolve within a few hours, and mild redness for 24 hours. Most clients return to normal activities immediately. We advise avoiding strenuous exercise, heat exposure, and alcohol for 24 hours post-treatment.

Profhilo Treatment London - Bio-Remodelling Skin Booster Marylebone

Profhilo is one of our most popular bio-remodelling treatments for skin laxity, dehydration, and loss of firmness. At Mesglo Aesthetic Clinic Marylebone, London, we use the BAP (Bio Aesthetic Points) injection technique to deliver one of the highest concentrations of hyaluronic acid available, stimulating four types of collagen and elastin for a natural lift and remodelling effect with no added volume.

Price: From £300 | Duration: 30-45 minutes | Results: Visible improvement in 2-4 weeks, optimal at 8 weeks

How Profhilo Works

Profhilo is injected at five specific Bio Aesthetic Points (BAP) on each side of the face. The ultra-pure hyaluronic acid then disperses beneath the skin, providing deep hydration and stimulating four different types of collagen and elastin. This bio-remodelling effect tightens and lifts the skin from within, without adding volume or changing facial structure.

Benefits

Intense, deep skin hydration
Improved skin firmness and elasticity
Natural lifting and tightening effect
Stimulates collagen and elastin production
Suitable for face, neck, hands, and decolletage
Quick treatment with minimal downtime

The Treatment Process

Skin assessment and consultation
Cleansing and marking of injection points
Precise injections at Bio Aesthetic Points
Post-treatment care instructions
Second session after 4 weeks for optimal results

Frequently Asked Questions

How many Profhilo sessions do I need?

The standard protocol is two sessions spaced 4 weeks apart. Maintenance treatments are recommended every 6 months to sustain the bio-remodelling benefits.

Is Profhilo suitable for all skin types?

Yes, Profhilo is suitable for all skin types and is particularly effective for those experiencing skin laxity, dehydration, or early signs of ageing. It is popular with clients aged 30 and above.

Is Profhilo Right for You?

Best suited for: Skin laxity, dehydration, loss of glow, crepey skin on the face, neck, hands, or décolletage. Ideal for clients who want natural skin quality improvement without added volume.
Not suitable for: This treatment may not be suitable during pregnancy or breastfeeding, with active skin infection in the treatment area, or with known hyaluronic acid sensitivity. Suitability is confirmed at consultation.
Possible side effects: Possible side effects vary depending on individual response. Small temporary bumps at injection sites, mild redness, or bruising may occur and typically resolve within 24 hours. Rahena will discuss your individual risk profile at consultation.
Consultation required: Rahena will assess suitability, treatment goals, medical history, and skin condition before recommending any treatment. See our Profhilo cost guide for pricing and course information.
Alternatives to consider: If volume restoration or structural definition is your goal, dermal fillers may be more appropriate. Profhilo pairs well with polynucleotide treatment for a comprehensive regenerative approach. Compare Profhilo vs hyaluronic acid fillers in our guide.

Complementary Treatments

Many clients combine Profhilo with polynucleotide face treatment for deeper cellular regeneration, or with exosome therapy for the most advanced regenerative approach. For preventative patients in their 30s, Profhilo is often the first step in a preventative aesthetic programme.

Book your Profhilo treatment at Mesglo London.

Visit Our Marylebone Clinic

Mesglo London is located in the heart of Marylebone, W1G, London — one of the capital's most prestigious neighbourhoods. Our clinic is easily accessible from Baker Street, Bond Street, and Regent's Park Underground stations.

View Mesglo London on Google Maps for directions, opening hours, and patient reviews.

Compare Profhilo with Other Treatments

Not sure if Profhilo is the right choice for you? Use our interactive comparison tool to see how Profhilo compares with other treatments at Mesglo London. Compare prices, downtime, results timelines, and more side by side.

Compare Profhilo with alternatives

What Our Clients Say

Rated 5.0 / 5 from verified Google reviews.

I finally found a clinic that delivers results I actually love. The Profhilo treatment has given my skin incredible hydration and firmness. The attention to detail made all the difference.

— Victoria S., verified Google review