Welcome to the future of aesthetic medicine. In the heart of London, a revolutionary treatment is transforming how we approach skin and hair rejuvenation. Polynucleotide therapy, a cutting-edge treatment harnessing the power of DNA fragments, is now available at Mesglo Aesthetic Clinic in Marylebone. This comprehensive guide will explore everything you need to know about this innovative therapy, from the science behind it to the remarkable results it can achieve.
What is Polynucleotide Therapy?
Polynucleotide therapy is a regenerative treatment that uses highly purified fragments of DNA to stimulate cellular repair and regeneration. These polynucleotides, derived from salmon DNA, are biocompatible with the human body and work at a cellular level to rejuvenate skin and hair. Unlike other treatments that simply mask symptoms, polynucleotide therapy addresses the root causes of ageing and hair loss, promoting long-lasting, natural-looking results.
| Feature | Description |
| Treatment Type | Injectable regenerative therapy |
| Source | Highly purified salmon DNA |
| Mechanism | Cellular repair and regeneration |
| Applications | Skin rejuvenation, hair loss treatment, anti-ageing |
| Results | Natural-looking, long-lasting |
| Downtime | Minimal |
At Mesglo Aesthetic Clinic, we are proud to offer this advanced treatment to our clients in Marylebone and across London. Our expert practitioners are highly trained in the latest polynucleotide techniques, ensuring you receive the safest, most effective treatment possible. To learn more about our polynucleotide treatments, please visit our Polynucleotide Face Treatment and Polynucleotide Hair Treatment pages.
The Science Behind Polynucleotide Therapy: How DNA Fragments Work
Polynucleotide therapy is grounded in the science of cellular regeneration. The highly purified DNA fragments used in this treatment work through two primary mechanisms: the A2 receptor stimulation pathway and the salvage pathway. These pathways work together to stimulate cellular repair, enhance blood flow, and promote the production of essential proteins like collagen and elastin.
The A2 Receptor Stimulation Pathway
This pathway is crucial for promoting angiogenesis, the formation of new blood vessels. When polynucleotides are introduced into the skin, they activate the A2 receptor, which in turn stimulates a cascade of cellular responses. This leads to the production of vascular endothelial growth factor (VEGF), a key protein responsible for creating new blood vessels. Enhanced blood flow delivers more oxygen and nutrients to the skin and hair follicles, promoting healthier, more vibrant tissues.
The Salvage Pathway
The salvage pathway is essential for recycling and reusing nucleotides, the building blocks of DNA. As our cells age, their ability to produce new DNA diminishes. The salvage pathway allows cells to recycle nucleotides from degraded DNA, ensuring a steady supply for cellular repair and replication. By providing a rich source of nucleotides, polynucleotide therapy enhances this natural process, promoting cellular regeneration and repair.
For a deeper dive into the science behind polynucleotides, we recommend reading our upcoming blog post: “Scientific Focus: Understanding Polynucleotides: How DNA Fragments Regenerate Skin and Hair”.
Benefits of Polynucleotide Therapy for Skin
Polynucleotide therapy offers a wide range of benefits for the skin, making it a versatile and effective treatment for various concerns. From reducing fine lines and wrinkles to improving skin texture and tone, this innovative therapy can help you achieve a more youthful, radiant complexion.
Comprehensive Skin Rejuvenation
Polynucleotide therapy stimulates the production of collagen and elastin, two essential proteins for maintaining skin firmness and elasticity. This leads to a significant improvement in skin texture, a reduction in fine lines and wrinkles, and a more lifted appearance. The treatment also enhances skin hydration, leaving your skin looking plump, healthy, and glowing.
| Benefit | Description |
| Collagen Stimulation | Increases production of new collagen fibres for improved firmness. |
| Elastin Enhancement | Restores skin elasticity and resilience. |
| Cellular Regeneration | Accelerates turnover of healthy skin cells. |
| Barrier Restoration | Strengthens the skin’s protective barrier function. |
| Hydration Optimization | Improves the skin’s ability to retain moisture. |
To learn more about how polynucleotide therapy can rejuvenate your skin, visit our Polynucleotide Face Treatment page. We also offer other advanced skin treatments, such as Exosome Face Treatment and Anti-wrinkle Treatment, which can be combined with polynucleotide therapy for enhanced results.
Benefits of Polynucleotide Therapy for Hair
Polynucleotide therapy is not just for skin; it is also a highly effective treatment for hair loss and thinning. By stimulating hair follicles and improving scalp health, this innovative therapy can help you achieve thicker, fuller, and healthier hair.
Comprehensive Hair Restoration
Polynucleotide therapy works by revitalizing dormant hair follicles and promoting the growth of new, healthy hair. The treatment improves blood circulation to the scalp, delivering essential nutrients to the hair follicles. This leads to a significant reduction in hair shedding, an increase in hair density, and an improvement in hair quality.
| Benefit | Description |
| Follicular Regeneration | Revitalizes dormant and weakened hair follicles. |
| Hair Density Improvement | Increases the number of active growing hairs. |
| Hair Quality Enhancement | Improves thickness, strength, and texture of individual hairs. |
| Scalp Health Optimization | Creates ideal environment for sustained hair growth. |
| Growth Cycle Regulation | Optimizes the natural hair growth cycle. |
If you are struggling with hair loss or thinning, our Polynucleotide Hair Treatment may be the solution you have been looking for. We also offer Exosome Hair Loss Treatment for a comprehensive approach to hair restoration.
The Complete History and Evolution of Polynucleotide Therapy
Polynucleotide therapy represents one of the most significant advances in regenerative medicine in recent decades. The journey began in the 1990s when researchers first discovered the regenerative properties of DNA fragments derived from salmon sperm. Initially used in wound healing applications, the therapy has evolved into a sophisticated aesthetic treatment that addresses the fundamental causes of skin ageing and hair loss.
The development of polynucleotide therapy for aesthetic applications began in South Korea, where researchers at leading universities conducted extensive studies on the biocompatibility and efficacy of salmon-derived DNA fragments. These early studies demonstrated remarkable results in cellular regeneration, leading to the development of the first commercial polynucleotide products for aesthetic use.
Today, polynucleotide therapy is recognised as one of the most advanced regenerative treatments available, with clinics across Europe, Asia, and North America offering this innovative therapy. At Mesglo Aesthetic Clinic in Marylebone, we are proud to be at the forefront of this revolutionary treatment, offering our clients access to the latest advances in polynucleotide technology.
Understanding the Different Types of Polynucleotide Treatments
Not all polynucleotide treatments are created equal. There are several different types of polynucleotide products available, each with its own unique properties and applications. Understanding these differences is crucial for achieving optimal results.
High Molecular Weight Polynucleotides
High molecular weight polynucleotides contain longer chains of DNA fragments, typically ranging from 50,000 to 2,000,000 Daltons. These products are particularly effective for deep tissue regeneration and are often used for more significant skin concerns such as deep wrinkles, severe sun damage, and advanced signs of ageing.
Low Molecular Weight Polynucleotides
Low molecular weight polynucleotides contain shorter DNA fragments, typically ranging from 50,000 to 350,000 Daltons. These products are ideal for superficial skin concerns such as fine lines, mild sun damage, and general skin quality improvement. They are also commonly used for preventative anti-ageing treatments in younger patients.
Ultra-Pure Polynucleotides
Ultra-pure polynucleotides undergo additional purification processes to remove any potential allergens or contaminants. These products are ideal for patients with sensitive skin or those who have experienced reactions to other aesthetic treatments. At Mesglo, we exclusively use ultra-pure polynucleotide products to ensure the highest level of safety and efficacy for our clients.
The Comprehensive Benefits of Polynucleotide Therapy
The benefits of polynucleotide therapy extend far beyond simple skin improvement. This revolutionary treatment offers a comprehensive approach to facial and scalp rejuvenation, addressing multiple concerns simultaneously.
Advanced Anti-Ageing Effects
Polynucleotide therapy provides some of the most advanced anti-ageing effects available in modern aesthetic medicine. By stimulating cellular regeneration at the DNA level, this treatment can reverse many of the visible signs of ageing, including:
Fine Line Reduction: Polynucleotides stimulate the production of new collagen fibres, which help to smooth out fine lines and prevent the formation of new ones. This effect is particularly noticeable around the eyes, mouth, and forehead, where fine lines tend to appear first.
Wrinkle Improvement: For deeper wrinkles, polynucleotides work by promoting collagen remodelling, a process that can significantly reduce the depth and appearance of established wrinkles. This is achieved through the activation of fibroblasts, the cells responsible for collagen production.
Texture Refinement: One of the most noticeable benefits of polynucleotide therapy is the improvement in skin texture. Patients often report that their skin feels smoother, softer, and more refined after treatment. This is due to the increased cellular turnover and improved hydration that polynucleotides provide.
Tone Correction: Polynucleotides can help to even out skin tone by reducing redness, minimising the appearance of age spots, and improving overall skin clarity. This is achieved through the anti-inflammatory properties of the treatment and its ability to promote healthy cellular function.
Practical Advantages Over Other Treatments
Polynucleotide therapy offers several practical advantages over other aesthetic treatments, making it an ideal choice for busy professionals and those seeking minimal downtime.
Minimal Downtime: Unlike surgical procedures or more aggressive treatments, polynucleotide therapy requires minimal downtime. Most patients can return to their normal activities within 24-48 hours of treatment, making it an ideal choice for those with busy lifestyles.
Natural Results: Because polynucleotides work with the body’s natural regenerative processes, the results are incredibly natural-looking. There is no risk of the “overdone” appearance that can sometimes occur with other treatments.
Progressive Improvement: The results of polynucleotide therapy continue to improve over time as the cellular regeneration process continues. This means that patients often see their best results several months after treatment.
Complementary Effects: Polynucleotide therapy works synergistically with other treatments, making it an excellent addition to a comprehensive aesthetic treatment plan. It can be combined with dermal fillers, anti-wrinkle treatments, and other procedures for enhanced results.
Polynucleotide Therapy for Specific Skin Concerns
Polynucleotide therapy is remarkably versatile and can be used to address a wide range of specific skin concerns. Understanding how this treatment can be tailored to your individual needs is key to achieving optimal results.
Acne Scarring and Skin Texture Issues
Acne scarring is one of the most challenging skin concerns to treat, but polynucleotide therapy has shown remarkable results in improving the appearance of acne scars. The treatment works by stimulating the production of new collagen and elastin, which helps to fill in depressed scars and smooth out the skin’s surface.
For patients with acne scarring, we typically recommend a series of 4-6 treatments spaced 3-4 weeks apart. The polynucleotides are injected directly into the scarred areas, where they work to stimulate cellular regeneration and promote the formation of new, healthy tissue.
Sun Damage and Hyperpigmentation
Sun damage is one of the primary causes of premature ageing, and polynucleotide therapy can be highly effective in reversing its effects. The treatment works by promoting cellular turnover, which helps to remove damaged cells and replace them with new, healthy ones.
For patients with sun damage, polynucleotide therapy can help to reduce the appearance of age spots, improve skin tone and texture, and restore a more youthful appearance. The treatment is particularly effective when combined with other skin rejuvenation treatments such as chemical peels or laser therapy.
Sensitive and Reactive Skin
Patients with sensitive or reactive skin often struggle to find effective aesthetic treatments that don’t cause irritation or adverse reactions. Polynucleotide therapy is an excellent option for these patients because it is naturally biocompatible and has anti-inflammatory properties.
The treatment can help to strengthen the skin’s barrier function, reduce sensitivity, and improve overall skin health. For patients with conditions such as rosacea or eczema, polynucleotide therapy can provide significant relief and improvement in symptoms.
The Complete Polynucleotide Hair Restoration Process
Hair loss affects millions of people worldwide, and traditional treatments often provide limited results. Polynucleotide therapy offers a revolutionary approach to hair restoration that addresses the root causes of hair loss and promotes the growth of new, healthy hair.
Understanding Hair Loss and Follicle Health
Hair loss occurs when hair follicles become damaged or dormant, leading to thinning hair and eventual baldness. This can be caused by a variety of factors, including genetics, hormonal changes, stress, and environmental damage. Polynucleotide therapy works by revitalising these damaged follicles and promoting the growth of new hair.
The treatment is particularly effective for androgenetic alopecia (male and female pattern baldness), which is the most common cause of hair loss. By improving blood circulation to the scalp and providing the essential building blocks for cellular regeneration, polynucleotides can help to reverse the effects of this condition.
The Hair Restoration Treatment Protocol
At Mesglo, we have developed a comprehensive hair restoration protocol using polynucleotide therapy. This protocol is based on the latest scientific research and our extensive clinical experience.
Initial Assessment: Every hair restoration journey begins with a thorough assessment of your scalp and hair. We use advanced diagnostic tools to evaluate the health of your hair follicles and determine the best treatment approach.
Treatment Planning: Based on your assessment, we will create a personalised treatment plan that may include polynucleotide therapy alone or in combination with other treatments such as exosome therapy.
Treatment Sessions: Most patients require a series of 4-6 treatment sessions spaced 2-3 weeks apart. During each session, polynucleotides are injected directly into the scalp using a series of small, precise injections.
Maintenance Protocol: To maintain optimal results, we typically recommend maintenance treatments every 6-12 months, depending on your individual needs and response to treatment.
Expected Results and Timeline
The results of polynucleotide hair restoration therapy are gradual and progressive, with most patients beginning to see improvements within 6-8 weeks of their first treatment. The full results typically become apparent after 3-6 months, as the hair growth cycle is naturally slow.
Weeks 1-4: During this initial period, patients may notice a reduction in hair shedding and an improvement in scalp health. The scalp may feel healthier and less irritated.
Weeks 4-8: New hair growth typically begins to become apparent during this period. The new hair is often finer and lighter in colour initially but will gradually become thicker and darker over time.
Months 3-6: The full results of treatment become apparent during this period. Patients typically see a significant increase in hair density, improved hair quality, and a healthier scalp.
Long-term Results: With proper maintenance, the results of polynucleotide hair restoration can last for many years. Many patients find that their hair continues to improve even after the initial treatment series is complete.
Cost Considerations and Treatment Investment
Understanding the investment required for polynucleotide therapy is important for making an informed decision about your treatment. At Mesglo, we believe in transparent pricing and will always provide you with a clear breakdown of costs during your consultation.
Factors Affecting Treatment Cost
Several factors can affect the cost of polynucleotide therapy, including:
Treatment Area: Larger treatment areas require more product and time, which can increase the overall cost. For example, treating the entire face will typically cost more than treating just the under-eye area.
Number of Sessions: Most patients require multiple treatment sessions to achieve optimal results. The total number of sessions needed will depend on your individual concerns and goals.
Product Type: Different types of polynucleotide products have different costs. Ultra-pure, high-quality products typically cost more but provide superior results and safety.
Practitioner Expertise: Treatment by highly experienced practitioners may cost more, but this investment often pays off in terms of superior results and safety.
Comparing Value with Other Treatments
When considering the cost of polynucleotide therapy, it’s important to compare it with other treatment options. While the initial investment may be higher than some alternatives, the long-lasting results and comprehensive benefits often make it a more cost-effective choice in the long run.
Compared to Surgery: Polynucleotide therapy costs significantly less than surgical procedures such as facelifts or hair transplants, while providing natural-looking results with minimal downtime.
Compared to Other Injectables: While polynucleotide therapy may cost more than basic dermal fillers, the regenerative benefits and longer-lasting results often provide better value for money.
Compared to Skincare Products: High-end skincare products can cost hundreds or thousands of pounds per year with limited results. Polynucleotide therapy provides more dramatic and longer-lasting improvements for a comparable investment.
Safety Profile and Potential Side Effects
Safety is our top priority at Mesglo Aesthetic Clinic, and we want all our clients to have a clear understanding of the safety profile of polynucleotide therapy. The good news is that this treatment has an excellent safety record when performed by qualified practitioners.
Common Side Effects
The most common side effects of polynucleotide therapy are mild and temporary, typically resolving within a few days of treatment:
Injection Site Reactions: Mild redness, swelling, or tenderness at the injection sites is normal and typically resolves within 24-48 hours. Applying ice and avoiding strenuous exercise can help minimise these effects.
Bruising: Some patients may experience minor bruising at the injection sites. This is more common in patients who take blood-thinning medications or supplements. Bruising typically resolves within 5-7 days.
Temporary Skin Sensitivity: Some patients may experience increased skin sensitivity for a few days after treatment. Using gentle skincare products and avoiding harsh treatments can help minimise this effect.
Rare Side Effects
Serious side effects from polynucleotide therapy are extremely rare when the treatment is performed by qualified practitioners using high-quality products:
Allergic Reactions: While polynucleotides are biocompatible, allergic reactions can occur in very rare cases. We always conduct a thorough medical history and may perform patch testing for patients with a history of allergies.
Infection: As with any injectable treatment, there is a small risk of infection. We follow strict sterile techniques and provide detailed aftercare instructions to minimise this risk.
Granuloma Formation: This is an extremely rare complication that can occur with any injectable treatment. It involves the formation of small nodules under the skin and typically requires medical treatment.
Contraindications and Precautions
Polynucleotide therapy is not suitable for everyone. We will carefully assess your medical history and current health status to ensure that the treatment is safe for you:
Pregnancy and Breastfeeding: We do not recommend polynucleotide therapy for pregnant or breastfeeding women as a precautionary measure.
Active Skin Infections: Treatment should be postponed if you have an active skin infection in the treatment area.
Autoimmune Conditions: Patients with certain autoimmune conditions may not be suitable candidates for treatment. We will assess each case individually.
Blood Clotting Disorders: Patients with bleeding disorders or those taking blood-thinning medications may have an increased risk of bruising and may not be suitable candidates.
Aftercare and Maximising Your Results
Proper aftercare is essential for achieving optimal results from polynucleotide therapy. At Mesglo, we provide detailed aftercare instructions and ongoing support to ensure that you get the best possible outcomes from your treatment.
Immediate Aftercare (First 24-48 Hours)
The first 24-48 hours after treatment are crucial for optimal healing and results:
Avoid Touching: Resist the urge to touch or massage the treated areas, as this can increase the risk of infection or displacement of the product.
Apply Ice: Gentle ice application can help reduce swelling and discomfort. Apply ice for 10-15 minutes at a time, several times throughout the day.
Avoid Strenuous Exercise: Intense physical activity can increase blood flow and potentially worsen swelling or bruising. Light activities such as walking are fine.
Sleep Elevated: Sleeping with your head slightly elevated can help reduce swelling, particularly if you’ve had treatment around the eyes.
Short-term Aftercare (First Week)
During the first week after treatment, continue to take care of your skin to ensure optimal healing:
Gentle Skincare: Use gentle, fragrance-free skincare products and avoid harsh treatments such as exfoliants or retinoids for at least a week.
Sun Protection: Protect your skin from sun exposure by using a broad-spectrum sunscreen with at least SPF 30. This is particularly important as your skin may be more sensitive than usual.
Avoid Heat: Avoid saunas, hot baths, and other sources of excessive heat, as these can increase swelling and discomfort.
Stay Hydrated: Drinking plenty of water helps support the healing process and can enhance your results.
Long-term Care and Maintenance
To maintain and enhance your results from polynucleotide therapy, consider the following long-term care strategies:
Regular Skincare Routine: Maintain a consistent skincare routine that includes cleansing, moisturising, and sun protection. High-quality skincare products can help support and enhance your results.
Healthy Lifestyle: A healthy diet, regular exercise, adequate sleep, and stress management all contribute to healthy skin and can help maintain your results.
Follow-up Treatments: Most patients benefit from maintenance treatments every 6-12 months to maintain optimal results. We will work with you to develop a maintenance schedule that fits your needs and budget.
Complementary Treatments: Consider combining polynucleotide therapy with other treatments such as mesotherapy or Lumi Eyes treatment for enhanced results.
Combining Polynucleotide Therapy with Other Treatments
One of the greatest advantages of polynucleotide therapy is its ability to work synergistically with other aesthetic treatments. At Mesglo, we often recommend combination treatment plans that can provide more comprehensive and dramatic results than any single treatment alone.
Polynucleotides and Dermal Fillers
Combining polynucleotide therapy with dermal fillers can provide both immediate and long-term benefits. While dermal fillers provide instant volume and contouring, polynucleotides work to improve skin quality and promote long-term regeneration.
This combination is particularly effective for comprehensive facial rejuvenation, where patients want both immediate improvement and long-term skin health benefits. The polynucleotides can help extend the longevity of dermal filler results by improving the overall health and quality of the skin.
Polynucleotides and Anti-Wrinkle Treatments
Anti-wrinkle treatments work by relaxing facial muscles to reduce dynamic wrinkles, while polynucleotides improve skin quality and reduce static wrinkles. Together, these treatments can provide comprehensive wrinkle reduction and prevention.
This combination is particularly effective for patients with both dynamic wrinkles (caused by muscle movement) and static wrinkles (caused by skin ageing). The anti-wrinkle treatment addresses the muscle component, while polynucleotides address the skin quality component.
Polynucleotides and Exosome Therapy
Both polynucleotides and exosome therapy are regenerative treatments that work at the cellular level. When combined, they can provide enhanced regenerative benefits and more dramatic results.
Exosomes work by facilitating cellular communication and promoting healing, while polynucleotides provide the building blocks for cellular regeneration. Together, they create a powerful regenerative treatment that can address even the most challenging skin concerns.
The Future of Polynucleotide Therapy
Polynucleotide therapy is a rapidly evolving field, with new developments and improvements being made regularly. At Mesglo, we stay at the forefront of these developments to ensure that our clients have access to the latest and most effective treatments.
Emerging Technologies and Techniques
Several exciting developments are on the horizon for polynucleotide therapy:
Targeted Delivery Systems: Researchers are developing new delivery systems that can target polynucleotides to specific cell types or skin layers, potentially improving efficacy and reducing side effects.
Combination Products: New products that combine polynucleotides with other active ingredients such as hyaluronic acid or peptides are being developed to provide enhanced benefits.
Personalised Treatments: Advances in genetic testing and personalised medicine may soon allow us to tailor polynucleotide treatments to each individual’s specific genetic profile and needs.
Research and Clinical Studies
Ongoing research continues to expand our understanding of polynucleotide therapy and its applications. Recent studies have explored the use of polynucleotides for:
Wound Healing: Research has shown that polynucleotides can accelerate wound healing and reduce scarring, leading to potential applications in post-surgical care and trauma treatment.
Hair Restoration: New studies are exploring the optimal protocols for using polynucleotides in hair restoration, including combination treatments and maintenance schedules.
Body Treatments: Researchers are investigating the use of polynucleotides for body treatments, including stretch mark reduction and skin tightening.
Conclusion: The Future of Regenerative Aesthetics
Polynucleotide therapy represents a significant advancement in aesthetic medicine. By harnessing the power of DNA fragments, this innovative treatment offers a safe, effective, and natural-looking solution for skin and hair rejuvenation. Whether you are looking to reduce the signs of ageing, improve your skin’s health, or restore thinning hair, polynucleotide therapy can help you achieve your goals.
At Mesglo Aesthetic Clinic in Marylebone, we are committed to providing our clients with the latest and most effective treatments. Our team of expert practitioners will work with you to create a personalized treatment plan that meets your unique needs. To learn more about polynucleotide therapy and our other advanced aesthetic treatments, please explore our website or contact us to schedule a consultation.
Book Your Consultation Today
Ready to experience the transformative power of polynucleotide therapy? Book your consultation today at our Marylebone clinic. Our expert team will assess your needs and create a personalized treatment plan to help you achieve your aesthetic goals. Visit our booking page or call us on 07830402077 to schedule your appointment.
References
1.Lee, K. W. A., Chan, K. W. L., Lee, A., Lee, C. H., Wan, J., Wong, S., & Yi, K. H. (2024). Polynucleotides in Aesthetic Medicine: A Review of Current Practices and Perceived Effectiveness. International Journal of Molecular Sciences, 25(15), 8224. https://doi.org/10.3390/ijms25158224
Comprehensive FAQ Section
What makes polynucleotide therapy different from other regenerative treatments?
Polynucleotide therapy is unique because it provides the actual building blocks (DNA fragments) that cells need for regeneration, rather than just signalling molecules or growth factors. This direct approach often leads to more predictable and consistent results compared to treatments that rely on the body’s own resources, which can vary significantly between individuals.
How do I know if I’m a good candidate for polynucleotide therapy?
Most adults who are concerned about skin ageing, hair loss, or skin quality issues are good candidates for polynucleotide therapy. The best way to determine if you’re a suitable candidate is to schedule a consultation at our Marylebone clinic, where we can assess your individual needs and medical history.
Can polynucleotide therapy be used preventatively?
Absolutely! Polynucleotide therapy is excellent for preventative anti-ageing. Many of our younger clients use polynucleotide therapy to maintain their skin health and prevent the early signs of ageing. Starting treatment in your late twenties or early thirties can help maintain optimal skin function and delay the onset of visible ageing.
How does polynucleotide therapy compare to PRP in terms of results?
While both treatments are regenerative, polynucleotide therapy often provides more consistent results because it doesn’t depend on the quality of your blood or your body’s ability to produce growth factors. Polynucleotides provide a standardised dose of regenerative material, making results more predictable. However, some patients benefit from combining both treatments for enhanced results.
Is there any downtime after polynucleotide therapy?
Downtime is minimal with polynucleotide therapy. Most patients experience only mild swelling and redness that resolves within 24-48 hours. You can typically return to work and normal activities immediately after treatment, though we recommend avoiding strenuous exercise for 24 hours.
How long do the results of polynucleotide therapy last?
Results typically last 6-12 months, but this can vary depending on individual factors such as age, skin condition, lifestyle, and the specific areas treated. Many patients find that their results continue to improve for several months after treatment as the regenerative process continues.
Can polynucleotide therapy help with acne scars?
Yes, polynucleotide therapy can be very effective for improving the appearance of acne scars. The treatment stimulates collagen production and cellular regeneration, which can help fill in depressed scars and improve overall skin texture. For severe scarring, we may recommend combining polynucleotide therapy with other treatments such as microneedling or laser therapy.
Is polynucleotide therapy suitable for all skin types?
Polynucleotide therapy is suitable for all skin types and ethnicities. The treatment is particularly beneficial for patients with sensitive skin who may not be able to tolerate other aesthetic treatments, as polynucleotides have anti-inflammatory properties and are naturally biocompatible.
What should I expect during my first polynucleotide treatment?
Your first treatment will begin with a thorough consultation and assessment. We’ll cleanse your skin and apply a topical numbing cream for comfort. The treatment itself involves a series of small injections using very fine needles. Most patients find the treatment comfortable, and the entire process typically takes 30-45 minutes.
Can I combine polynucleotide therapy with my regular skincare routine?
Yes, polynucleotide therapy works well with most skincare routines. In fact, maintaining a good skincare routine can help enhance and prolong your results. We’ll provide specific recommendations based on your skin type and the treatments you’ve received.
How soon can I see results from polynucleotide therapy?
While some patients notice improvements in skin texture and hydration within a few weeks, the full regenerative effects typically become apparent after 6-8 weeks. Results continue to improve for several months as the cellular regeneration process continues.
Is polynucleotide therapy worth the investment?
Many patients find polynucleotide therapy to be an excellent investment in their skin health and appearance. While the initial cost may be higher than some other treatments, the long-lasting results and comprehensive benefits often provide excellent value for money. Additionally, the preventative benefits can help reduce the need for more invasive treatments in the future.
To learn more about polynucleotide therapy and whether it’s right for you, we invite you to schedule a consultation at our Marylebone clinic. Our expert team will assess your individual needs and create a personalised treatment plan to help you achieve your aesthetic goals.