How many treatments will I need?

For optimal results, we typically recommend a course of 3-4 treatments, spaced 4-6 weeks apart. However, the exact number of sessions will depend on your individual skin concerns and goals. Many clients notice a significant improvement in their skin after just one treatment.

Is the treatment painful?

We apply a topical numbing cream before the procedure to minimise any discomfort. Most clients report feeling only a slight vibrating sensation during the treatment.

What is the downtime?

Following the treatment, your skin will likely be red and may feel slightly sensitive, similar to a mild sunburn. This typically subsides within 24-48 hours. The use of exosomes can help to reduce the downtime compared to microneedling alone.

When will I see results?

Some initial results, such as a healthy glow, may be visible within a few days of the treatment. However, the full benefits of collagen remodelling will become apparent over the following weeks and months, with optimal results typically seen around 3-6 months after completing your course of treatments.

Is microneedling with exosomes safe?

Yes, when performed by a qualified and experienced practitioner, this is a very safe treatment. The exosomes used are rigorously tested and sterilised to ensure their purity and safety. At Mesglo London, we adhere to the highest standards of safety and hygiene.

What is the cost of the treatment?

At our Marylebone clinic, prices for microneedling start from £250. The combined treatment of microneedling with exosomes starts from £450. A personalised quote will be provided during your consultation.

Can this treatment be combined with other procedures?

Yes, microneedling with exosomes can be combined with other treatments to further enhance your results. For example, it can be alternated with treatments like mesotherapy or polynucleotides for a comprehensive skin rejuvenation programme. Our practitioners can create a bespoke treatment plan for you.

Who is a good candidate for this treatment?

This treatment is suitable for most skin types and can benefit anyone looking to improve the health and appearance of their skin. It is particularly effective for those with concerns about acne scars, fine lines, wrinkles, and uneven skin texture. A consultation is necessary to determine if you are a suitable candidate.

Microneedling with Exosomes: The Future of Skin Rejuvenation in Marylebone, London

Written by Rahena, Level 7 Aesthetic Practitioner | Mesglo London

In the heart of London, the quest for radiant, youthful skin is a common goal. While countless treatments promise to turn back the clock, one combination stands out for its remarkable, science-backed results: microneedling with exosomes. At Mesglo London, our Marylebone clinic specialises in this advanced skin rejuvenation therapy, offering a transformative experience that goes beyond surface-level treatments. This article will delve into the science behind microneedling and exosomes, explaining how this powerful duo can address a wide range of skin concerns and why it is considered the ultimate skin rejuvenation treatment in London.

Key Takeaways

Microneedling, or Collagen Induction Therapy, stimulates the skin’s natural healing process to produce more collagen and elastin, improving skin texture and firmness.
Exosomes are powerful messengers that contain growth factors and proteins that can significantly enhance cellular regeneration and tissue repair.
Combining microneedling with exosomes allows for deeper penetration of these regenerative molecules, amplifying the treatment’s effectiveness and leading to superior results.
This combination therapy can effectively treat a wide range of skin concerns, including acne scars, fine lines, wrinkles, enlarged pores, and uneven skin texture.
The treatment is suitable for most skin types and offers a minimally invasive solution for those seeking significant and lasting improvements in their skin’s health and appearance.

The Science of Microneedling: More Than Just Needles

Microneedling, also known as Collagen Induction Therapy (CIT), is a minimally invasive cosmetic procedure that has gained immense popularity for its impressive skin rejuvenation capabilities. The treatment involves using a device equipped with fine, sterile needles to create thousands of controlled micro-injuries in the skin. This process might sound intimidating, but it is the key to unlocking the skin’s natural regenerative potential.

When the skin is punctured, it triggers a three-phase healing response:

The depth of the needles can be adjusted depending on the specific skin concern being treated. For instance, deeper needle penetration is often required for treating acne scars, while more superficial depths are used for general skin rejuvenation and improving the appearance of fine lines. Our practitioners at Mesglo London are highly trained to customise the treatment to each client’s unique needs, ensuring optimal results for those seeking 'microneedling London' treatments.

**Inflammation:** Immediately after the procedure, the body’s natural defence mechanism is activated. This results in increased blood flow to the area, which helps to disinfect the wounds and prepare the skin for repair.
**Proliferation:** In this phase, the body begins to produce new cells, including fibroblasts, which are responsible for creating collagen and elastin. This new tissue growth helps to fill in the micro-wounds.
**Remodelling:** Over the following weeks and months, the newly formed collagen and elastin mature and reorganise, leading to a firmer, smoother, and more youthful-looking complexion. The new collagen helps to reduce the appearance of scars, fine lines, and wrinkles.

What Are Exosomes? The Future of Skin Regeneration

Exosomes represent a groundbreaking advancement in the field of regenerative medicine and aesthetics. These are not cells, but rather nano-sized vesicles that are released by cells, particularly stem cells. They act as messengers, facilitating communication between cells and playing a vital role in tissue repair and regeneration.

Exosomes are packed with a powerful cargo of bioactive molecules, including:

In aesthetic treatments, the exosomes used are typically derived from mesenchymal stem cells (MSCs), which are known for their potent regenerative properties. These exosomes are rigorously purified and sterilised to ensure their safety and efficacy. When applied to the skin, they provide a concentrated boost of regenerative signals, encouraging the skin to repair and renew itself from within. For a more in-depth understanding, you can read our complete guide to exosome therapy.

**Growth Factors:** These proteins stimulate cell growth, proliferation, and differentiation, promoting the repair of damaged tissues.
**Proteins:** Essential for building and repairing tissues, proteins are a key component of healthy skin.
**Lipids:** These help to maintain the skin’s barrier function, keeping it hydrated and protected from environmental damage.
**Nucleic Acids (mRNA, microRNA):** These molecules can influence gene expression in the recipient cells, encouraging them to behave in a more youthful and healthy manner.

The Power Couple: Why Microneedling and Exosomes Work Better Together

The combination of microneedling and exosomes is a true game-changer in the world of skin rejuvenation. While each treatment is effective on its own, their synergistic action produces results that are far superior to what either can achieve alone.

Microneedling creates thousands of microscopic channels in the skin. These channels act as direct pathways, allowing for the enhanced absorption of topical treatments. When exosomes are applied to the skin immediately after a microneedling session, they can penetrate deep into the dermis, where they can exert their regenerative effects most effectively.

This combination provides a dual-action approach to skin rejuvenation:

This powerful synergy results in a more robust and accelerated healing response, leading to more dramatic and longer-lasting improvements in skin quality. The downtime is also often reduced, as the exosomes help to calm inflammation and promote faster recovery.

Feature	Microneedling Alone	Microneedling with Exosomes
Collagen Stimulation	Good	Excellent
Reduction in Downtime	Standard	Faster
Improvement in Skin Texture	Visible	Significantly Enhanced
Reduction of Pigmentation	Moderate	Superior
Overall Rejuvenation	Effective	Transformative

**Microneedling initiates the healing cascade:** The micro-injuries created by the needles signal to the body that repair is needed, stimulating the production of new collagen and elastin.
**Exosomes provide the building blocks for repair:** The growth factors, proteins, and other molecules within the exosomes provide the skin with the necessary resources to carry out this repair process more efficiently and effectively.

What Skin Concerns Can Be Treated?

Microneedling with exosomes is a versatile treatment that can address a wide array of skin concerns, making it a popular choice for individuals seeking comprehensive skin rejuvenation in Marylebone. At Mesglo London, we use this advanced therapy to treat:

For those with deeper scars or more significant signs of ageing, a course of treatments is often recommended to achieve the best possible results. Our practitioners will work with you to create a personalised treatment plan tailored to your specific goals.

**Acne Scars:** By stimulating collagen production, the treatment helps to fill in and smooth out atrophic acne scars, leading to a more even skin surface.
**Fine Lines and Wrinkles:** The boost in collagen and elastin helps to plump the skin, reducing the appearance of fine lines and wrinkles, particularly around the eyes and mouth.
**Enlarged Pores:** Microneedling can help to tighten the skin and reduce the size of enlarged pores, giving the complexion a more refined appearance.
**Uneven Skin Tone and Texture:** The treatment promotes cellular turnover and renewal, leading to a smoother, more even, and more radiant skin tone.
**Sun Damage and Pigmentation:** Exosomes can help to regulate melanin production, reducing the appearance of sunspots and other forms of hyperpigmentation.
**Overall Skin Health:** Even if you do not have specific concerns, this treatment can improve the overall health and vitality of your skin, giving it a beautiful, youthful glow.

The Mesglo London Protocol: Your Treatment Journey

At Mesglo London, your comfort, safety, and results are our top priorities. Our protocol for microneedling with exosomes is designed to provide a seamless and effective treatment experience from start to finish.

Treatment Component	Description	Duration
Consultation	Skin assessment and discussion of goals.	30 minutes
Numbing	Application of a topical anaesthetic cream.	20-30 minutes
Microneedling	The microneedling procedure itself.	20-30 minutes
Exosome Application	Application of the exosome serum.	5 minutes
Total Treatment Time		75-95 minutes

**Consultation:** Your journey begins with a thorough consultation with one of our expert practitioners. We will assess your skin, discuss your concerns and goals, and determine if this treatment is the right choice for you. We will also explain the procedure in detail and answer any questions you may have.
**Preparation:** On the day of your treatment, your skin will be thoroughly cleansed, and a topical numbing cream will be applied to ensure your comfort throughout the procedure.
**Microneedling:** Once the numbing cream has taken effect, your practitioner will use a professional-grade microneedling device to create micro-injuries across the treatment area. The needle depth will be adjusted based on your specific skin concerns.
**Exosome Application:** Immediately after the microneedling is complete, a highly concentrated exosome serum is applied to the skin. The micro-channels created by the needles allow for optimal absorption of the serum.
**Aftercare:** Following the treatment, we will provide you with detailed aftercare instructions to ensure a smooth recovery and optimal results. This will include advice on which skincare products to use and what to avoid in the days following your procedure.

Microneedling with Exosomes vs. Other Regenerative Treatments

While microneedling with exosomes is a highly effective treatment, it is important to understand how it compares to other regenerative therapies available. Two popular alternatives are Platelet-Rich Plasma (PRP) therapy and Polynucleotides.

At Mesglo London, we offer a range of regenerative treatments, and our experts can help you choose the one that is best suited to your individual needs and goals. We believe in a personalised approach to aesthetics, ensuring that each client receives the most effective and appropriate care.

**PRP Therapy:** This treatment involves drawing a sample of your own blood, processing it to concentrate the platelets, and then injecting the PRP back into the skin. While PRP contains growth factors, the concentration and quality can vary depending on the individual’s health and age. Exosomes, on the other hand, provide a consistent and highly concentrated source of regenerative molecules.
**Polynucleotides:** These are long chains of nucleotides that work by stimulating fibroblasts and improving the overall health of the skin. They are excellent for hydration and repair, but they do not provide the same broad spectrum of growth factors and proteins as exosomes. You can learn more about the differences in our article, Polynucleotides vs. PRP: Which is Better?.

Conclusion

Microneedling with exosomes represents the pinnacle of modern skin rejuvenation, offering a powerful and effective solution for a wide range of skin concerns. By combining the collagen-stimulating effects of microneedling with the regenerative power of exosomes, this treatment delivers transformative results that are both visible and long-lasting. If you are ready to experience the ultimate in skin rejuvenation, we invite you to visit us at Mesglo London in Marylebone. Our team of expert practitioners is dedicated to helping you achieve your skin goals and revealing a more radiant, youthful you.

Frequently Asked Questions

How many treatments will I need?: For optimal results, we typically recommend a course of 3-4 treatments, spaced 4-6 weeks apart. However, the exact number of sessions will depend on your individual skin concerns and goals. Many clients notice a significant improvement in their skin after just one treatment.
Is the treatment painful?: We apply a topical numbing cream before the procedure to minimise any discomfort. Most clients report feeling only a slight vibrating sensation during the treatment.
What is the downtime?: Following the treatment, your skin will likely be red and may feel slightly sensitive, similar to a mild sunburn. This typically subsides within 24-48 hours. The use of exosomes can help to reduce the downtime compared to microneedling alone.
When will I see results?: Some initial results, such as a healthy glow, may be visible within a few days of the treatment. However, the full benefits of collagen remodelling will become apparent over the following weeks and months, with optimal results typically seen around 3-6 months after completing your course of treatments.
Is microneedling with exosomes safe?: Yes, when performed by a qualified and experienced practitioner, this is a very safe treatment. The exosomes used are rigorously tested and sterilised to ensure their purity and safety. At Mesglo London, we adhere to the highest standards of safety and hygiene.
What is the cost of the treatment?: At our Marylebone clinic, prices for microneedling start from £250. The combined treatment of microneedling with exosomes starts from £450. A personalised quote will be provided during your consultation.
Can this treatment be combined with other procedures?: Yes, microneedling with exosomes can be combined with other treatments to further enhance your results. For example, it can be alternated with treatments like mesotherapy or polynucleotides for a comprehensive skin rejuvenation programme. Our practitioners can create a bespoke treatment plan for you.
Who is a good candidate for this treatment?: This treatment is suitable for most skin types and can benefit anyone looking to improve the health and appearance of their skin. It is particularly effective for those with concerns about acne scars, fine lines, wrinkles, and uneven skin texture. A consultation is necessary to determine if you are a suitable candidate.