Mesglo London

Mesotherapy Explained: The Science Behind Skin Rejuvenation Cocktails

Mesotherapy Explained

At Mesglo Aesthetic Clinic in Marylebone, discover how Mesotherapy restores hydration, radiance, and youthfulness from within.

What Is Mesotherapy?

Mesotherapy is one of the most effective, science-driven ways to rejuvenate the skin without surgery.
Developed in France in the 1950s, it involves injecting a customised cocktail of vitamins, amino acids, minerals, antioxidants, and hyaluronic acid directly into the skin’s middle layer — the mesoderm.

Unlike topical creams that can only work on the surface, Mesotherapy acts where true regeneration happens, reactivating the skin’s natural repair mechanisms and improving hydration, tone, and elasticity.

💎 At Mesglo Aesthetic Clinic in Marylebone, London, we specialise in medical-grade Mesotherapy using advanced formulas designed to deliver visible, natural, and long-lasting results.


🧬 How Mesotherapy Works

The treatment works through two complementary actions — biochemical nourishment and mechanical stimulation.

  1. Biochemical action:
    The nutrient solution feeds and energises skin cells, stimulating fibroblasts to produce collagen and elastin.
  2. Mechanical action:
    The micro-injections themselves trigger a controlled healing response, encouraging tissue renewal and improving microcirculation.

Together, these processes revitalise the skin from the inside out, enhancing hydration, smoothness, and luminosity.


🧠 What’s Inside a Mesotherapy Cocktail?

Each formula is tailored to your skin’s needs. While ingredients may vary, a typical Mesotherapy blend at Mesglo includes:

IngredientPurposeVisible Effect
Hyaluronic AcidDeep hydrationPlumper, smoother skin
Vitamin CBrightening and antioxidant protectionMore even tone and radiance
Amino AcidsCollagen synthesisImproved elasticity
MineralsStrengthen barrierBalanced, healthier complexion
PeptidesCellular communicationFirmer, rejuvenated texture

🌸 Every treatment at Mesglo is bespoke — your practitioner will analyse your skin and create a formula to address specific concerns such as dullness, dehydration, pigmentation, or loss of firmness.


💧 Benefits of Mesotherapy for Skin Rejuvenation

Mesotherapy is suitable for both face and body, delivering visible, cumulative benefits.

✨ Key advantages:

  • Boosts hydration at a cellular level
  • Improves texture and tone for smoother, clearer skin
  • Stimulates collagen and elastin production
  • Restores radiance and glow
  • Reduces fine lines and early signs of ageing
  • Brightens dull or tired skin
  • Safe for all skin types

Many clients describe their skin as “refreshed, dewy and alive again” after just one treatment — with progressive improvement after a short course.


🔬 Mesotherapy vs Other Rejuvenation Treatments

At Mesglo, Mesotherapy is often compared to other skin-enhancing treatments such as skin boosters, polynucleotides, and exosomes.
While all improve skin quality, Mesotherapy has its unique place in a comprehensive rejuvenation plan.

TreatmentBest ForMechanismResults
MesotherapyHydration, tone, textureNutrient micro-injectionsGradual glow and firmness
Skin BoostersDeep hydrationHyaluronic acid gelPlumper, more elastic skin
PolynucleotidesRegenerationDNA fragments stimulating fibroblastsProgressive tissue renewal
ExosomesCellular communicationNano-messenger deliveryBrightness, repair, clarity

🔗 You can learn more about our complementary regenerative options on our Skin Quality Treatments Guide (link to relevant pillar).


🕊️ The Mesglo Approach: Precision, Care & Customisation

Mesglo has become one of London’s top-reviewed clinics for advanced skin rejuvenation because every treatment is guided by expertise and genuine artistry.

  • Personalised formulas: created according to your skin profile and lifestyle.
  • Medical-grade technique: ensuring even distribution and optimal absorption.
  • Holistic consultation: assessing diet, hydration, and stress factors that influence your skin’s health.

Your practitioner will guide you through every stage — from your first consultation to aftercare — making sure your treatment feels comfortable, safe, and deeply restorative.


💬 What to Expect During Treatment

1. Consultation & Assessment

Your practitioner examines your skin and designs a customised rejuvenation blend.

2. Preparation

The skin is cleansed and numbed with topical anaesthetic for maximum comfort.

3. Micro-injection Phase

Tiny injections deliver the nutrient solution evenly across the face, neck, or hands.

4. Recovery & Results

You may experience mild redness for a few hours. Within days, your skin appears more hydrated, supple, and radiant.

Results continue to build over 2–4 sessions, with maintenance treatments recommended every 3–6 months for sustained luminosity.


🧴 Post-Treatment Care

To optimise your results:

  • Avoid makeup or active skincare for 24 hours
  • Keep skin hydrated and use a broad-spectrum SPF daily
  • Avoid intense heat (saunas, steam) for 48 hours
  • Follow your personalised aftercare plan from your Mesglo practitioner

📍 Why Choose Mesglo in Marylebone for Mesotherapy

Located in the heart of Marylebone, Mesglo Aesthetic Clinic has rapidly earned a reputation for exceptional precision and naturally radiant outcomes.

Every treatment is performed by highly qualified practitioners with advanced training in regenerative aesthetics, ensuring results that are as safe as they are beautiful.

💬 Mesglo is trusted by clients across London for its artistry, scientific integrity, and focus on skin health rather than superficial trends.


Frequently Asked Questions

1. Is Mesotherapy painful?
A topical anaesthetic is applied to ensure comfort. Most clients describe it as a light tingling sensation.

2. How long do results last?
Hydration and glow can last 3–6 months, depending on lifestyle and skincare. Regular sessions prolong and enhance results.

3. Can Mesotherapy be combined with other treatments?
Yes — it pairs beautifully with skin boosters, exosomes, or laser treatments for comprehensive rejuvenation.

4. How soon can I wear makeup after treatment?
We recommend waiting 24 hours to allow the skin to heal and absorb nutrients fully.

5. Is Mesotherapy suitable for men?
Absolutely. Mesotherapy is an excellent option for men seeking refreshed, healthy-looking skin without downtime.


🌟 Book Your Consultation at Mesglo

Ready to experience smoother, brighter, more hydrated skin?
Book your Mesotherapy consultation in Marylebone, London today and let our expert practitioners tailor the perfect rejuvenation plan for you.

🩵 Mesglo London — where science meets artistry for naturally radiant skin.

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