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Nasolabial Fold Treatment in Marylebone, London: Dermal Fillers, Polynucleotides and Regenerative Options

Written by , Level 7 Aesthetic Practitioner | Mesglo London

Discover the most effective treatments for nasolabial folds in London. From dermal fillers to regenerative options like polynucleotides and Profhilo, our expert guide covers causes, treatments, and costs to help you achieve a more youthful appearance. Book your consultation at our Marylebone clinic.

Understanding Nasolabial Folds: More Than Just Smile Lines

Nasolabial folds, often referred to as smile or laugh lines, are the natural creases that run from the sides of your nose to the corners of your mouth. While they are a normal part of our facial anatomy, these lines can become more pronounced over time, contributing to an aged or tired appearance. It is a common misconception that these folds are solely caused by smiling or laughing; in reality, their development is a complex process influenced by a combination of factors including genetics, sun exposure, and the natural ageing process. As we age, our skin loses collagen and elastin, the proteins responsible for its firmness and elasticity. This, coupled with a decrease in facial fat and bone density, can lead to sagging skin and the deepening of these facial lines. For those seeking a solution in London, Mesglo, a premier aesthetic clinic in Marylebone, offers a range of advanced treatments to soften these folds and restore a more youthful contour to the face.

What Causes Nasolabial Folds to Deepen?

The prominence of nasolabial folds is not solely a result of repetitive facial expressions. Several anatomical changes contribute to their appearance. A key factor is the loss of volume in the mid-face, particularly the cheeks. As the fat pads in our cheeks diminish and descend, the overlying skin loses its support and begins to sag, creating a more prominent fold. Furthermore, the natural decline in collagen and elastin production as we age reduces the skin's ability to bounce back, leading to the formation of static lines that are visible even when the face is at rest. Lifestyle factors such as smoking and excessive sun exposure can accelerate this process by damaging the skin's structural proteins. Understanding these underlying causes is the first step towards identifying the most effective treatment approach for your unique needs.

Dermal Fillers: The Gold Standard for Nasolabial Folds

Dermal fillers are a cornerstone of modern aesthetic medicine and remain one of the most popular and effective treatments for nasolabial folds. At Mesglo London, we specialise in using hyaluronic acid (HA) based fillers, a substance that naturally occurs in the body and is known for its hydrating and volumising properties. When strategically injected into the nasolabial fold area, or the adjacent cheek region to provide lift, dermal fillers can instantly smooth out creases, restore lost volume, and create a more refreshed and youthful appearance. The procedure is minimally invasive, with results that are both immediate and natural-looking. Our expert practitioners in Marylebone tailor each treatment to the individual, ensuring a result that enhances your natural beauty without looking overdone. To learn more about how dermal fillers can address your concerns, explore our comprehensive [dermal fillers guide](/blog/dermal-fillers-london-complete-guide/).

Types of Dermal Fillers for Nasolabial Folds

Not all dermal fillers are created equal. Different formulations are designed to address specific concerns, from fine lines to deep-set wrinkles and significant volume loss. The choice of filler depends on your unique anatomy and desired outcome. At Mesglo London, we utilise a range of premium fillers to ensure a bespoke treatment. Below is a comparison of common filler types used for nasolabial folds.

The Dermal Filler Treatment Process

Your journey to smoother skin begins with a thorough consultation at our London clinic. During this session, our practitioners will assess your facial anatomy, discuss your aesthetic goals, and determine the most appropriate type and amount of filler for your needs. The treatment itself is relatively quick, typically lasting around 30 minutes. A topical anaesthetic is applied to ensure your comfort, and the filler is then carefully injected into the targeted areas. You can expect to see an immediate improvement in the appearance of your nasolabial folds, with minimal downtime. Some temporary redness, swelling, or bruising at the injection site is normal and typically subsides within a few days. The results of dermal filler treatments for nasolabial folds can last from 6 to 18 months, depending on the type of filler used and individual factors such as metabolism.

Regenerative Treatments: The Future of Facial Rejuvenation

While dermal fillers offer an excellent solution for volume loss, regenerative treatments are gaining popularity for their ability to improve skin quality from within. These innovative therapies stimulate the body's own natural healing and regenerative processes to produce long-lasting improvements in skin texture, firmness, and elasticity. At Mesglo London, we are at the forefront of this exciting field, offering cutting-edge treatments like Polynucleotides and Profhilo. These treatments work by providing the skin with the building blocks it needs to repair and rejuvenate itself, offering a more holistic approach to anti-ageing. For those looking for the [best anti-ageing treatments in London](/blog/best-anti-ageing-treatments-london/), regenerative options are a powerful tool in our arsenal.

Polynucleotides: Bio-Stimulation for Natural Results

Polynucleotides are a revolutionary injectable treatment that harnesses the power of highly purified DNA fragments to bio-stimulate the skin. Unlike dermal fillers that simply add volume, polynucleotides work at a cellular level to boost collagen and elastin production, improve hydration, and protect the skin from free radical damage. This results in a gradual and natural-looking improvement in skin quality, making it an excellent option for treating nasolabial folds, particularly when skin laxity is a primary concern. A course of [polynucleotide treatments](/polynucleotide-face-london/) at our W1 clinic can lead to firmer, more radiant skin with a visible reduction in the depth of nasolabial folds. The treatment is suitable for all skin types and offers a safe and effective way to achieve a more youthful appearance.

Profhilo: The Injectable Moisturiser

Profhilo is another groundbreaking bio-remodelling treatment that has taken the aesthetics world by storm. It is not a filler, but rather a unique hyaluronic acid-based injectable that spreads like honey beneath the skin, providing intense hydration and stimulating the production of four different types of collagen and elastin. This 'injectable moisturiser' is particularly effective for improving overall skin quality and laxity, which can in turn soften the appearance of nasolabial folds. A [Profhilo treatment](/profhilo-treatment-london/) at Mesglo London involves a series of small injections and can significantly improve skin tone, texture, and firmness. It is an ideal treatment for those who are not yet ready for dermal fillers but want to address the early signs of ageing and improve the overall health of their skin.

Choosing the Right Treatment for You: A Comparison

With several effective options available, choosing the right treatment for your nasolabial folds can seem daunting. The best approach often depends on the primary cause of your folds, whether it be volume loss, skin laxity, or a combination of both. Dermal fillers are the go-to solution for replacing lost volume and providing immediate correction. Regenerative treatments like Polynucleotides and Profhilo, on the other hand, are excellent for improving skin quality and stimulating long-term collagen production. In many cases, a combination approach yields the most comprehensive and satisfying results. Our experts at Mesglo London will guide you through the options and help you create a personalised treatment plan that aligns with your goals.

TreatmentPrimary TargetOnset of ResultsDuration of ResultsPrice (from)
Dermal FillersVolume LossImmediate6-18 months£350
PolynucleotidesSkin Laxity & QualityGradual (weeks)6-12 months£350
ProfhiloSkin Laxity & HydrationGradual (weeks)6 months£350

Combination Therapy: The Ultimate Approach

For many of our clients in Marylebone and across London, the most effective way to address nasolabial folds is through combination therapy. This involves layering different treatments to tackle the various aspects of facial ageing simultaneously. For example, we might use dermal fillers to restore volume to the cheeks and lift the mid-face, which in turn softens the nasolabial folds. This can then be complemented with a course of polynucleotide or Profhilo treatments to improve the overall quality and tightness of the skin. This multi-faceted approach allows us to achieve a truly harmonious and natural-looking rejuvenation, addressing both the symptoms and the underlying causes of facial ageing. At Mesglo, we believe in creating bespoke treatment plans that are as unique as you are.

At Mesglo London, we often find that a combination of treatments delivers the most superior and long-lasting results for nasolabial folds. By using dermal fillers to restore volume and regenerative treatments like polynucleotides to improve skin quality, we can achieve a truly comprehensive and natural-looking rejuvenation.

What to Expect: Results, Recovery, and Aftercare

The results of your nasolabial fold treatment will vary depending on the chosen therapy. With dermal fillers, you will see an immediate improvement, although the final result will become apparent after a week or two once any swelling has subsided. For regenerative treatments, the results are more gradual, appearing over several weeks as your skin begins to produce new collagen and elastin. Recovery from all of these treatments is minimal, with most clients able to return to their normal activities immediately. You may experience some mild redness, swelling, or bruising, but this can be easily concealed with makeup. We will provide you with detailed aftercare instructions to ensure you get the best possible results from your treatment.

Conclusion

Nasolabial folds are a common concern, but they don't have to be a permanent one. With the advanced and effective treatments available at Mesglo London, you can soften these lines and restore a more youthful and refreshed appearance. Whether you opt for the immediate volumising effects of dermal fillers or the long-term skin rejuvenation of regenerative treatments, our team of experts is here to guide you every step of the way. We invite you to book a consultation at our clinic in the heart of Marylebone to discover how we can help you achieve your aesthetic goals. Your journey to a more confident and radiant you starts here.

Frequently Asked Questions

Are nasolabial fold treatments painful?
We take every measure to ensure your comfort during treatment. A topical anaesthetic is applied before dermal filler injections, and the fillers themselves often contain a local anaesthetic. Polynucleotide and Profhilo injections are administered with very fine needles and are generally well-tolerated.
How long do the results of nasolabial fold treatments last?
The longevity of your results will depend on the treatment you choose. Dermal filler results can last from 6 to 18 months, while the benefits of regenerative treatments like polynucleotides and Profhilo can last for up to a year. Maintenance treatments are recommended to preserve your results.
Are there any side effects to these treatments?
Side effects are typically mild and temporary. They may include redness, swelling, bruising, or tenderness at the injection site. Serious complications are rare when treatment is performed by a qualified and experienced practitioner.
How much does nasolabial fold treatment cost in London?
The cost of treatment will vary depending on the type and amount of product used. At Mesglo London, prices for nasolabial fold treatments start from £350. We will provide you with a detailed cost breakdown during your consultation.
Which treatment is right for me?
The best treatment for you will depend on your individual needs and aesthetic goals. During your consultation at our Marylebone clinic, we will conduct a thorough assessment and recommend the most suitable treatment plan for you. We encourage you to explore our [dermal fillers page](/dermal-fillers/) for more information.

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